[HTML][HTML] RIG-I-induced innate antiviral immunity protects mice from lethal SARS-CoV-2 infection
S Marx, BM Kümmerer, C Grützner, H Kato… - … Therapy-Nucleic Acids, 2022 - cell.com
The SARS-CoV-2 pandemic has underscored the need for rapidly usable prophylactic and
antiviral treatments against emerging viruses. The targeted stimulation of antiviral innate …
antiviral treatments against emerging viruses. The targeted stimulation of antiviral innate …
[HTML][HTML] An AAAG-rich oligodeoxynucleotide rescues mice from bacterial septic peritonitis by interfering interferon regulatory factor 5
S Gao, X Li, S Nie, L Yang, L Tu, B Dong… - International Journal of …, 2017 - mdpi.com
A previous study found that an AAAG-rich Oligodeoxynucleotide (ODN), designated as
MS19, could lessen the acute lung inflammatory injury (ALII) in mice infected by influenza …
MS19, could lessen the acute lung inflammatory injury (ALII) in mice infected by influenza …
[HTML][HTML] SARS-CoV-2 nucleocapsid protein targets RIG-I-like receptor pathways to inhibit the induction of interferon response
SJ Oh, OS Shin - Cells, 2021 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the coronavirus disease 2019 (COVID-19) that has resulted in the current pandemic. The …
the coronavirus disease 2019 (COVID-19) that has resulted in the current pandemic. The …
[HTML][HTML] The downregulation of microRNA hsa-miR-340-5p in IAV-infected A549 cells suppresses viral replication by targeting RIG-I and OAS2
L Zhao, X Zhang, Z Wu, K Huang, X Sun… - … Therapy-Nucleic Acids, 2019 - cell.com
The influenza A virus poses serious public health challenges worldwide. Strikingly, small
noncoding microRNAs (miRNAs) that modulate gene expression are closely involved in …
noncoding microRNAs (miRNAs) that modulate gene expression are closely involved in …
Knockdown of different influenza A virus subtypes in cell culture by a single antisense oligodeoxyribonucleotide
AS Levina, MN Repkova, NA Mazurkova… - International Journal of …, 2015 - Elsevier
Influenza is a heavy socially significant viral infection that affects humans, birds, and wild
and domestic animals. The threat of existing and new highly pathogenic subtypes of …
and domestic animals. The threat of existing and new highly pathogenic subtypes of …
[HTML][HTML] The effects of the Xijiao Dihuang decoction combined with Yinqiao powder on miRNA-mRNA profiles in mice infected with influenza a virus
K Li, X Chen, J Zhong, H Ye, S Zhang, D Ge… - … Medicine and Therapies, 2020 - Springer
Background MicroRNAs (miRNAs) play vital roles in acute inflammatory and antiviral
responses during influenza A virus (IAV) infection. The Xijiao Dihuang decoction combined …
responses during influenza A virus (IAV) infection. The Xijiao Dihuang decoction combined …
[HTML][HTML] ISCOM-like Nanoparticles Formulated with Quillaja brasiliensis Saponins Are Promising Adjuvants for Seasonal Influenza Vaccines
M Rivera-Patron, M Moreno, M Baz, PM Roehe… - Vaccines, 2021 - mdpi.com
Vaccination is the most effective public health intervention to prevent influenza infections,
which are responsible for an important burden of respiratory illnesses and deaths each year …
which are responsible for an important burden of respiratory illnesses and deaths each year …
Monophosphoryl lipid A-adjuvanted nucleoprotein-neuraminidase nanoparticles improve immune protection against divergent influenza viruses
Universal influenza vaccines are urgently needed to prevent recurrent influenza epidemics
and inevitable pandemics. We generated double-layered protein nanoparticles …
and inevitable pandemics. We generated double-layered protein nanoparticles …
Apigenin suppresses influenza A virus‐induced RIG‐I activation and viral replication
X Xu, J Miao, Q Shao, Y Gao… - Journal of medical …, 2020 - Wiley Online Library
Apigenin is a flavonoid of low toxicity and multiple beneficial bioactivities, including the
properties of antitumor, antioxidant, anti‐inflammatory, and antiviral activities. However, the …
properties of antitumor, antioxidant, anti‐inflammatory, and antiviral activities. However, the …
Toll-like receptor-4 (TLR4) agonist-based intranasal nanovaccine delivery system for inducing systemic and mucosal immunity
MA Bakkari, CK Valiveti, RS Kaushik… - Molecular …, 2021 - ACS Publications
Eliciting a robust immune response at mucosal sites is critical in preventing the entry of
mucosal pathogens such as influenza and severe acute respiratory syndrome coronavirus 2 …
mucosal pathogens such as influenza and severe acute respiratory syndrome coronavirus 2 …