Both genomic instability and the presence of chronic inflammation are involved in
carcinogenesis and tumor progression. These alterations predispose the cancer cells to …

Ferroptosis is a recently recognized form of non-apoptotic regulated cell death and usually
driven by iron-dependent lipid peroxidation and has arisen to play a significant role in …

Iron-dependent lipid peroxidation causes ferroptosis, a form of regulated cell death. Crucial
steps in the formation of ferroptosis include the accumulation of ferrous ions (Fe2+) and lipid …

The discovery of regulated cell death processes has enabled advances in cancer treatment.
In the past decade, ferroptosis, an iron-dependent form of regulated cell death driven by …

Ferroptosis is an iron-dependent, nonapoptotic form of regulated cell death triggered by
impaired redox and antioxidant machinery and propagated by the accumulation of toxic lipid …

Ferroptosis is a non-apoptotic form of regulated cell death characterized by the lethal
accumulation of iron-dependent membrane-localized lipid peroxides. It acts as an innate …

In cancer treatment, the recurrent challenge of inducing apoptosis through conventional
therapeutic modalities, often thwarted by therapy resistance, emphasizes the critical need to …

Ferroptosis is a newly defined form of cell death induced by iron-dependent accumulation of
lethal lipid peroxidation. Ferroptosis represent a therapeutic strategy to suppress therapy …

Ferroptosis is a recently described programmed cell death mechanism that is characterized
by the buildup of iron (Fe)-dependent lipid peroxides in cells and is morphologically …

Introduction Ferroptosis, a form of programmed cell death, is mediated primarily by lipid
peroxidation via a unique iron-dependent process. The mechanisms of ferroptosis involve …