Recruitment of the 4EHP-GYF2 cap-binding complex to tetraproline motifs of tristetraprolin promotes repression and degradation of mRNAs with AU-rich elements
The zinc finger protein tristetraprolin (TTP) promotes translation repression and degradation
of mRNAs containing AU-rich elements (AREs). Although much attention has been directed …
of mRNAs containing AU-rich elements (AREs). Although much attention has been directed …
Novel mRNA targets for tristetraprolin (TTP) identified by global analysis of stabilized transcripts in TTP-deficient fibroblasts
WS Lai, JS Parker, SF Grissom, DJ Stumpo… - … and cellular biology, 2006 - Taylor & Francis
Tristetraprolin (TTP) is a tandem CCCH zinc finger protein that was identified through its
rapid induction by mitogens in fibroblasts. Studies of TTP-deficient mice and cells derived …
rapid induction by mitogens in fibroblasts. Studies of TTP-deficient mice and cells derived …
Phosphorylation of Tristetraprolin, a Potential Zinc Finger Transcription Factor, by Mitogen Stimulation in Intact Cells and by Mitogen-activated Protein Kinase in Vitro∗
GA Taylor, MJ Thompson, WS Lai… - Journal of Biological …, 1995 - ASBMB
Tristetraprolin (TTP) is a potential transcription factor that contains three PPPPG repeats and
two putative CCCH zinc fingers. TTP is encoded by the early response gene Zfp-36, which is …
two putative CCCH zinc fingers. TTP is encoded by the early response gene Zfp-36, which is …
Chromatin modification and global transcriptional silencing in the oocyte mediated by the mRNA decay activator ZFP36L2
JN Chousal, K Cho, M Ramaiah, D Skarbrevik… - Developmental cell, 2018 - cell.com
Global transcriptional silencing is a highly conserved mechanism central to the oocyte-to-
embryo transition. We report the unexpected discovery that global transcriptional silencing in …
embryo transition. We report the unexpected discovery that global transcriptional silencing in …
Modulation of immediate early gene expression by tristetraprolin in the differentiation of 3T3-L1 cells
NY Lin, CT Lin, CJ Chang - Biochemical and biophysical research …, 2008 - Elsevier
Tristetraprolin (TTP) is a zinc-finger-containing AU-rich elements (ARE)-binding protein.
AREs presented in the 3′ untranslated region (UTR) of mRNAs from many proto …
AREs presented in the 3′ untranslated region (UTR) of mRNAs from many proto …
Ablation of ZC3H11A causes early embryonic lethality and dysregulation of metabolic processes
S Younis, A Jouneau, M Larsson… - Proceedings of the …, 2023 - National Acad Sciences
ZC3H11A (zinc finger CCCH domain–containing protein 11A) is a stress-induced mRNA-
binding protein required for efficient growth of nuclear-replicating viruses. The cellular …
binding protein required for efficient growth of nuclear-replicating viruses. The cellular …
Interactions of CCCH zinc finger proteins with mRNA: non-binding tristetraprolin mutants exert an inhibitory effect on degradation of AU-rich element-containing …
WS Lai, EA Kennington, PJ Blackshear - Journal of Biological Chemistry, 2002 - ASBMB
Tristetraprolin (TTP), the prototype of a small family of CCCH tandem zinc finger (TZF)
domain proteins, is a physiological stimulator of instability of the mRNAs encoding tumor …
domain proteins, is a physiological stimulator of instability of the mRNAs encoding tumor …
Comparative expression of tristetraprolin (TTP) family member transcripts in normal human tissues and cancer cell lines
DM Carrick, PJ Blackshear - Archives of biochemistry and biophysics, 2007 - Elsevier
The tristetraprolin (TTP) family of tandem zinc finger proteins comprises three members in
man and most other mammals, with a fourth expressed in rodents. In mice, gene disruption …
man and most other mammals, with a fourth expressed in rodents. In mice, gene disruption …
Mitogens stimulate the rapid nuclear to cytosolic translocation of tristetraprolin, a potential zinc-finger transcription factor.
GA Taylor, MJ Thompson, WS Lai… - Molecular …, 1996 - academic.oup.com
Tristetraprolin (TTP) is the prototype of a group of potential transcription factors that contain
two or more unusual CCCH zinc fingers. TTP is encoded by the immediate-early response …
two or more unusual CCCH zinc fingers. TTP is encoded by the immediate-early response …
[PDF][PDF] RETRACTED: elevated tristetraprolin impairs trophoblast invasion in women with recurrent miscarriage by destabilization of HOTAIR
FJ Tian, XY He, J Wang, X Li, XL Ma, F Wu… - … Therapy-Nucleic Acids, 2018 - cell.com
Tristetraprolin (TTP) regulates the stability of multiple targets that have important biological
roles. However, the role of TTP in trophoblasts at the maternal-fetal interface remains poorly …
roles. However, the role of TTP in trophoblasts at the maternal-fetal interface remains poorly …