Tumor suppressor p53 plays a key role in induction of both tristetraprolin and let-7 in human cancer cells
JY Lee, HJ Kim, NA Yoon, WH Lee, YJ Min… - Nucleic acids …, 2013 - academic.oup.com
Abstract Tristetraprolin (TTP) and let-7 microRNA exhibit suppressive effects on cell growth
through down-regulation of oncogenes. Both TTP and let-7 are often repressed in human …
through down-regulation of oncogenes. Both TTP and let-7 are often repressed in human …
Glucocorticoids regulate tristetraprolin synthesis and posttranscriptionally regulate tumor necrosis factor alpha inflammatory signaling
K Smoak, JA Cidlowski - Molecular and cellular biology, 2006 - Am Soc Microbiol
Glucocorticoids are used to treat various inflammatory disorders, but the mechanisms
underlying these actions are incompletely understood. The zinc finger protein tristetraprolin …
underlying these actions are incompletely understood. The zinc finger protein tristetraprolin …
[HTML][HTML] Identification of Zfp393, a germ cell-specific gene encoding a novel zinc finger protein
Using the digital differential display program of the National Center for Biotechnology
Information, we identified a contig of expression sequence tags (ESTs) which were unique to …
Information, we identified a contig of expression sequence tags (ESTs) which were unique to …
Luteinizing hormone-induced connexin 43 down-regulation: inhibition of translation
Y Kalma, I Granot, D Galiani, A Barash, N Dekel - Endocrinology, 2004 - academic.oup.com
The coordinated function of the different compartments of the follicle, the oocyte and the
somatic cumulus/granulosa cells, is enabled by the presence of a network of cell-to-cell …
somatic cumulus/granulosa cells, is enabled by the presence of a network of cell-to-cell …
A Cys3His Zinc-Binding Domain from Nup475/Tristetraprolin: A Novel Fold with a Disklike Structure
BT Amann, MT Worthington, JM Berg - Biochemistry, 2003 - ACS Publications
Nup475 (also known as tristetraprolin and TIS11) includes two zinc-binding domains of the
form Cys-X8-Cys-X5-Cys-X3-His. These domains are required for rapid degradation of …
form Cys-X8-Cys-X5-Cys-X3-His. These domains are required for rapid degradation of …
The human TTP protein: sequence, alignment with related proteins, and chromosomal localization of the mouse and human genes.
GA Taylor, WS Lai, RJ Oakey, MF Seldin… - Nucleic acids …, 1991 - ncbi.nlm.nih.gov
The mouse tristetraprolin (TTP) protein is a basic proline-rich protein of Mr 33,600 that
contains three PPPPG repeats (1). Its mRNA levels increase dramatically after stimulation …
contains three PPPPG repeats (1). Its mRNA levels increase dramatically after stimulation …
[HTML][HTML] Histone deacetylase inhibitors activate tristetraprolin expression through induction of early growth response protein 1 (EGR1) in colorectal cancer cells
C Sobolewski, S Sanduja, FF Blanco, L Hu, DA Dixon - Biomolecules, 2015 - mdpi.com
The RNA-binding protein tristetraprolin (TTP) promotes rapid decay of mRNAs bearing
3'UTR AU-rich elements (ARE). In many cancer types, loss of TTP expression is observed …
3'UTR AU-rich elements (ARE). In many cancer types, loss of TTP expression is observed …
[HTML][HTML] RNA-binding protein ZFP36L2 downregulates Helios expression and suppresses the function of regulatory T cells
S Makita, H Takatori, A Iwata, S Tanaka… - Frontiers in …, 2020 - frontiersin.org
The zinc finger protein 36-like 2, ZFP36L2, is a member of a small family of RNA-binding
proteins composed by ZFP36 (also known as tristetraprolin, TTP), ZFP36L1 and ZFP36L2 in …
proteins composed by ZFP36 (also known as tristetraprolin, TTP), ZFP36L1 and ZFP36L2 in …
A dominant loss-of-function GJA1 (Cx43) mutant impairs parturition in the mouse
D Tong, X Lu, HX Wang, I Plante, E Lui… - Biology of …, 2009 - academic.oup.com
Expression of GJA1 (commonly known as connexin43 or Cx43), a major myometrial gap
junction protein, is upregulated before the onset of delivery, suggesting an essential role for …
junction protein, is upregulated before the onset of delivery, suggesting an essential role for …
[HTML][HTML] The mRNA decay factor tristetraprolin (TTP) induces senescence in human papillomavirus-transformed cervical cancer cells by targeting E6-AP ubiquitin …
S Sanduja, V Kaza, DA Dixon - Aging (Albany NY), 2009 - ncbi.nlm.nih.gov
The RNA-binding protein tristetraprolin (TTP) regulates expression of many cancer-
associated and proinflammatory factors through binding AU-rich elements (ARE) in the 3' …
associated and proinflammatory factors through binding AU-rich elements (ARE) in the 3' …