Cerium oxide nanoparticles as a new neuroprotective agent to promote functional recovery in a rat model of sciatic nerve crush injury

M Soluki, F Mahmoudi, A Abdolmaleki… - British Journal of …, 2024 - Taylor & Francis
Background Peripheral nerve injury is a common clinical disorder. The aim of the present
study was to investigate the role of cerium oxide nanoparticles on axonal regeneration and …

Injection of cerium oxide nanoparticles to treat spinal cord injury in rats

Z Behroozi, B Rahimi, MR Hamblin… - … of Neuropathology & …, 2022 - academic.oup.com
This study investigated the effects of local injection of cerium oxide nanoparticles (CeONPs)
in a rat spinal cord injury (SCI) model. Thirty-six adult male Wistar rats were divided into 4 …

Functional recovery of contused spinal cord in rat with the injection of optimal‐dosed cerium oxide nanoparticles

JW Kim, C Mahapatra, JY Hong, MS Kim… - Advanced …, 2017 - Wiley Online Library
Spinal cord injury (SCI) produces excess reactive oxygen species (ROS) that can
exacerbate secondary injury and lead to permanent functional impairment. Hypothesizing …

Study of nerve cell regeneration on nanofibers containing cerium oxide nanoparticles in a spinal cord injury model in rats

B Rahimi, Z Behroozi, A Motamednezhad… - Journal of Materials …, 2023 - Springer
Since the CNS is unable to repair itself via neuronal regeneration in adult mammals,
alternative therapies need to be found. The use of cerium oxide nanoparticles to repair …

Cerium oxide nanoparticles in neuroprotection and considerations for efficacy and safety

BA Rzigalinski, CS Carfagna… - Wiley Interdisciplinary …, 2017 - Wiley Online Library
Cerium oxide nanoparticles have widespread use in the materials industry, and have
recently come into consideration for biomedical use due to their potent regenerative …

Ultrasmall polymer-coated cerium oxide nanoparticles as a traumatic brain injury therapy

DW Kang, BG Cha, JH Lee, W Yang, SK Ki… - … , Biology and Medicine, 2022 - Elsevier
No medication has been approved for secondary injuries after traumatic brain injury (TBI).
While free radicals are considered a major mediator of secondary injury, conventional …

Neuroprotective mechanisms of cerium oxide nanoparticles in a mouse hippocampal brain slice model of ischemia

AY Estevez, S Pritchard, K Harper, JW Aston… - Free Radical Biology …, 2011 - Elsevier
Cerium oxide nanoparticles (nanoceria) are widely used as catalysts in industrial
applications because of their potent free radical-scavenging properties. Given that free …

Application of green-synthesized cerium oxide nanoparticles to treat spinal cord injury and cytotoxicity evaluation on paediatric leukaemia cells

W Yiling, GK Murakonda… - Materials Research …, 2021 - iopscience.iop.org
Injury prognosis, and treatment are one of the major objectives of nursing care during the
treatment of spinal cord injury (SCI). Here, we developed a novel, biocompatible Cerium …

Antioxidant and toxicity studies of biosynthesized cerium oxide nanoparticles in rats

MB Khorrami, HR Sadeghnia, A Pasdar… - International journal …, 2019 - Taylor & Francis
Purpose The purpose of this study was to investigate the acute toxic potential of cerium
oxide nanoparticles (CNPs) synthesized by pullulan in adult male Wistar rats. Patients and …

Shape effect of cerium oxide nanoparticles on mild traumatic brain injury

DH Youn, NM Tran, BJ Kim, Y Kim, JP Jeon, H Yoo - Scientific Reports, 2021 - nature.com
The catalytic performance and therapeutic effect of nanoparticles varies with shape. Here,
we investigated and compared the therapeutic outcomes of ceria nanospheres (Ceria NSs) …