“When offered to participate”: a systematic review and meta-analysis of patient agreement to participate in cancer clinical trials

JM Unger, DL Hershman, C Till… - JNCI: Journal of the …, 2021 - academic.oup.com
Background Patient participation in clinical trials is vital for knowledge advancement and
outcomes improvement. Few adult cancer patients participate in trials. Although patient …

Participation in cancer clinical trials: why are patients not participating?

MM Byrne, SL Tannenbaum, S Glück… - Medical Decision …, 2014 - journals.sagepub.com
Background. Participation in cancer clinical trials is low, particularly in racial and ethnic
minorities in some cases, which has negative consequences for the generalizability for study …

Barriers to participation in clinical trials of cancer: a meta-analysis and systematic review of patient-reported factors

EJ Mills, D Seely, B Rachlis, L Griffith, P Wu… - The lancet …, 2006 - thelancet.com
Background Enrolling participants onto clinical trials of cancer presents an important
challenge. We aimed to identify the concerns of patients with cancer about, and the barriers …

Systematic review and meta-analysis of the magnitude of structural, clinical, and physician and patient barriers to cancer clinical trial participation

JM Unger, R Vaidya, DL Hershman… - JNCI: Journal of the …, 2019 - academic.oup.com
Background Barriers to cancer clinical trial participation have been the subject of frequent
study, but the rate of trial participation has not changed substantially over time. Studies often …

[HTML][HTML] Barriers to participation in clinical trials: a physician survey

A Mahmud, O Zalay, A Springer, K Arts… - Current …, 2018 - pmc.ncbi.nlm.nih.gov
Background Clinical trials are vital for evidence-based cancer care. Oncologist engagement
in clinical trials has an effect on patient recruitment, which in turn can affect trial success …

A systematic review highlights threats to validity in studies of barriers to cancer trial participation

D Fayter, C McDaid, A Eastwood - Journal of clinical epidemiology, 2007 - Elsevier
OBJECTIVE: To investigate the barriers, modifiers, and benefits involved in participating in
randomized controlled trials of cancer therapies as perceived by health care providers and …

Why patients don't take part in cancer clinical trials: an overview of the literature

K Cox, J McGarry - European journal of cancer care, 2003 - Wiley Online Library
Why patients don't take part in cancer clinical trials: an overview of the literature Clinical
trials have been recognized extensively within the literature as a crucial component in the …

[HTML][HTML] Role of clinical trial participation in cancer research: barriers, evidence, and strategies

JM Unger, E Cook, E Tai, A Bleyer - American Society of Clinical …, 2016 - ncbi.nlm.nih.gov
Fewer than 1 in 20 adult cancer patients enroll in cancer clinical trials. But although barriers
to trial participation have been the subject of frequent study, the rate of trial participation has …

Barriers to clinical trial participation as perceived by oncologists and patients

NJ Meropol, JS Buzaglo, J Millard, N Damjanov… - Journal of the National …, 2007 - jnccn.org
Although clinical trial research is required for the development of improved treatment
strategies, very few cancer patients participate in these studies. The purpose of this study …

Patients' willingness to participate in clinical trials and their views on aspects of cancer research: results of a prospective patient survey

SY Moorcraft, C Marriott, C Peckitt, D Cunningham… - Trials, 2016 - Springer
Background Recruitment to clinical trials can be challenging and slower than anticipated.
This prospective patient survey aimed to investigate the proportion of patients approached …