Evidence of oxidative stress is apparent in both acute and chronic neurodegenerative
diseases, such as stroke, Parkinson's disease (PD) and amyotrophic lateral sclerosis (ALS) …

Superoxide dismutase (SOD) has now been known for 35 years. While the superoxide
radical and SOD have been implicated in many disease states including inflammatory …

In recent years, oxidative stress has been implicated in a variety of degenerative processes,
diseases, and syndromes. Some of these include atherosclerosis, myocardial infarction …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder that causes
motoneuron degeneration, paralysis and death. Mutations in Cu, Zn superoxide dismutase …

(minireview). J Physiol Biochem, 65 (2), 195-208, 2009. Reactive oxygen species (ROS) are
known participants in several cellular processes. Superoxide anion radical, one example of …

Superoxide dismutases (SODs) constitute a very important antioxidant defense against
oxidative stress in the body. The enzyme acts as a good therapeutic agent against reactive …

Oxidative stress, resulting from mitochondrial dysfunction, excitotoxicity, or
neuroinflammation, is implicated in numerous neurodegenerative conditions. Damage due …

Aging is the biggest risk factor for developing many neurodegenerative disorders, including
idiopathic Parkinson's disease (PD). PD is still an incurable disorder and the available …

Significance: Half a century of research provided unambiguous proof that superoxide and
species derived from it—reactive oxygen species (ROS)—play a central role in many …

Oxidative stress has become widely viewed as an underlying condition in a number of
diseases, such as ischemia–reperfusion disorders, central nervous system disorders …