In utero exposure to dicyclohexyl and di-n-hexyl phthalate possess genotoxic effects on testicular cells of male rats after birth in the comet and TUNEL assays

MA Ahbab, Ü Ündeğer, N Barlas… - Human & experimental …, 2014 - journals.sagepub.com
Phthalates are diester derivatives of phthalic acid widely used in many commercial
applications. The aim of this study is therefore to evaluate possible genotoxicity of di-n-hexyl …

From the Cover: Teratogenic Effects of in Utero Exposure to Di-(2-Ethylhexyl)-Phthalate (DEHP) in B6:129S4 Mice

E Ungewitter, E Rotgers, T Bantukul… - Toxicological …, 2017 - academic.oup.com
Intrauterine exposure to phthalates is known to cause disorders of male reproductive
function including androgen insufficiency, decreased fertility, and germ cell defects in …

Genotoxic, histologic, immunohistochemical, morphometric and hormonal effects of di-(2-ethylhexyl)-phthalate (DEHP) on reproductive systems in pre-pubertal male …

G Karabulut, N Barlas - Toxicology Research, 2018 - academic.oup.com
Abstract Di-(2-ethylhexyl) phthalate (DEHP) is widely used as a plasticizer and people are
exposed to various amounts on a daily basis. This study was designed to evaluate the …

Effect of in utero exposure to di-(2-ethylhexyl) phthalate: distribution in the rat fetus and testosterone production by rat fetal testis in culture

T Stroheker, JF Regnier, J Lassurguere… - Food and chemical …, 2006 - Elsevier
DEHP is known to cause reproductive toxicity in rats, particularly during the neonatal period.
Pregnant and brood rats were treated by gavage with 750mg/kgb. w./day DEHP starting on …

A Dose-Response Study Following In Utero and Lactational Exposure to Di(2-ethylhexyl)phthalate: Effects on Female Rat Reproductive Development

SW Grande, AJM Andrade, CE Talsness… - Toxicological …, 2006 - academic.oup.com
Phthalates, a class of chemicals used as plasticizers, are economically important due to
several industrial applications. Di (2-ethylhexyl) phthalate (DEHP) is the most commonly …

[HTML][HTML] Long-term effects of maternal exposure to Di (2-ethylhexyl) Phthalate on sperm and testicular parameters in Wistar rats offspring

M Dorostghoal, AA Moazedi… - Iranian journal of …, 2012 - ncbi.nlm.nih.gov
Background: Phthalate esters have been shown to cause reproductive toxicity in both
developing and adult animals. Objective: This study was designed to assess long-term …

Effect of mono-(2-ethylhexyl) phthalate on human and mouse fetal testis: In vitro and in vivo approaches

V Muczynski, JP Cravedi, A Lehraiki, C Levacher… - Toxicology and applied …, 2012 - Elsevier
The present study was conducted to determine whether exposure to the mono-(2-ethylhexyl)
phthalate (MEHP) represents a genuine threat to male human reproductive function. To this …

A dose response study following in utero and lactational exposure to di-(2-ethylhexyl) phthalate (DEHP): reproductive effects on adult male offspring rats

AJM Andrade, SW Grande, CE Talsness, C Gericke… - Toxicology, 2006 - Elsevier
The reproductive effects of in utero and lactational exposure to di-(2-ethylhexyl) phthalate
(DEHP) in adult male offspring rats were investigated. The selected endpoints included …

Dose-Response Assessment of Fetal Testosterone Production and Gene Expression Levels in Rat Testes Following InUtero Exposure to Diethylhexyl Phthalate …

BR Hannas, CS Lambright, J Furr… - Toxicological …, 2011 - academic.oup.com
Several phthalate esters have been linked to the Phthalate Syndrome, affecting male
reproductive development when administered to pregnant rats during in utero sexual …

Functional and Morphological Reproductive Aspects in Male Rats Exposed to Di-n-Butyl Phthalate (DBP) in Utero and During Lactation

WR Scarano, FC Toledo, MT Guerra… - Journal of Toxicology …, 2010 - Taylor & Francis
The potential adverse reproductive effects, with emphasis on the epididymis, of in utero and
lactational exposure to 100 mg/kg/d di-n-butyl phthalate (DBP) in adult male rat offspring …