Despite improvements in functional outcomes attributable to advances in radiotherapy,
chemotherapy, surgical techniques, and imaging techniques, survival in head and neck …

Molecular targeted therapy in head and neck squamous cell carcinoma (HNSCC) continues
to make strides, and holds much promise. Cetuximab remains the sole US FDA-approved …

Head and neck squamous cell carcinomas (HNSCCs) are an aggressive, genetically
complex and difficult to treat group of cancers. In lieu of truly effective targeted therapies …

Head and neck cancers are a heterogeneous, aggressive and genetically complex
collection of malignancies of the oral cavity, nasopharynx, oropharynx, hypopharynx, larynx …

Objective To provide a review of emerging knowledge from genomics and related basic
science, preclinical, and clinical precision medicine studies in head and neck squamous cell …

The genomic landscape of head and neck squamous cell carcinoma (HNSCC) has been
recently elucidated. Key epigenetic and genetic characteristics of this cancer have been …

The 20th century saw great advances in anatomy‐based (surgery and radiotherapy) and
chemotherapy approaches for treating head and neck squamous cell carcinoma (HNSCC) …

Head and neck squamous cell carcinoma (HNSCC) encompasses a diverse group of
malignancies originating in the oral cavity, oropharynx, larynx and hypopharynx. Although …

Cell lines are important tools for biological and preclinical investigation, and establishing
their relationship to genomic alterations in tumors could accelerate functional and …

Simple Summary Head and neck cancer remains a significant burden on patients and global
health systems. Traditional approaches to therapy have included surgery, and more recently …