Suramin is a polysulfonated naphthylurea, which was originally synthesized and designed
as a treatment for trypanosomiasis and selected malignancies and metastatic diseases …

Suramin is a polysulfonated naphthylurea originally designed as a treatment for
trypanosomiasis; but that has also been used to treat rodent models of fulminant hepatic …

Background Recently, we demonstrated that suramin, a compound that inhibits the
interaction of multiple cytokines/growth factors with their receptors, inhibits activation and …

AIM: Suramin is a symmetrical polysulfonated naphthylamine derivative of urea. There have
been few studies on the effect of suramin on cytokines. We examined the effects of suramin …

Apoptosis is the first cellular response of the liver to many toxic events, including viral
hepatitis, alcohol-induced liver disease and ischaemia/reperfusion injury. When apoptosis is …

Suramin inhibits the proliferation of several human tumors in vivo and in vitro. In this study,
the effects of Suramin on proliferation and angiogenesis were investigated in human …

Purpose: To investigate the cytotoxic activity of suramin against HepG2 human HCC cell
line. Methods: HepG2 cells were treated with 15, 30 and 45 µM suramin. HepG2 cell …

The antiparasitic drug, suramin, has antiproliferative effects in human carcinoma cells. It has
been suggested that this occurs through blockade of growth factor-receptor interactions …

Suramin has shown promising antitumour activity against several tumour types, both in vitro
and in vivo, but the clinical utility of this compound is hampered by its unfavourable toxicity …

Suramin, a polysulfonated naphthylurea, is an antitrypanosomal and antifilarial drug.
Because of its anti-reverse transcriptase activity and antiproliferative activity, suramin is also …