Carbon monoxide (CO) exposure at high concentrations results in overt neurotoxicity.
Exposure to low CO concentrations occurs commonly yet is usually sub-clinical. Infants are …

Laparoscopic surgery techniques have been increasingly preferred to classic laparotomy by
surgeons since 1987. However, this method may have some side effects on different …

Object: The authors studied the influence of CO 2 pneumoperitoneum on intracellular pH
and signal transduction arising from cancer cell multiplication in laparoscopic tumor …

Neuroblastoma is a type of pediatric cancer. The sensitivity of neuroblastoma (NB) cancer
cells to chemotherapy and radiation is inhibited by the presence of antioxidants, such as …

We previously reported that rat pheochromocytoma PC12 cells express the neuronal
differentiated phenotype under hyperoxia through the production of reactive oxygen species …

During mammalian embryo development in vitro, mechanism of embryonic development
arrest caused by oxidative stress has not been clear so far. The tumor suppressor protein …

Generation of reactive oxygen species (ROS) is an important mode of action of many
chemotherapeutic agents. Hydrogen peroxide (H2O2) is a model oxidant that has been …

Over the last decades, the silent-killer carbon monoxide (CO) has been shown to also be an
endogenous cytoprotective molecule able to inhibit cell death and modulate mitochondrial …

Background Oxidative stress is an important factor in the modulation of both tumorigenesis
and anticancer responses. Ozone (O 3) is a strong oxidant that causes redox reactions and …

In order to reveal neurodegeneration elicited by reactive oxygen intermediates (ROI),
neuronally differentiated cells from mouse embryonal carcinoma P19 cell line were exposed …