Oxidative stress-induced cytotoxicity in cervical cancer cells may be of toxicological interest.
In the present study, the effects of exogenous H2O2 on cell growth and death in HeLa …

Modulation of cerebral cell metabolism for improving the outcome of hypoxia-ischemia and
reperfusion is a strategy yet to be explored. Because carbon monoxide (CO) is known to …

In our previous study, we examined radiation-induced ROS formation, oxidative DNA
damage, early apoptotic changes, and mitochondrial membrane dysfunction in the human …

The premature increase of oxygen tension may contribute to oligodendroglial precursor cell
(OPC) damage in preterm infants. Fetal OPCs are exposed to low oxygen tissue tensions not …

Hypoxia is associated with the increased malignancy of a broad range of solid tumours.
While very severe hypoxia has been widely shown to induce cell cycle arrest, the impact of …

Hydrogen peroxide (H2O2) induces a number of events, which are also induced by
mitogens. Since the progression through the G1 phase of the cell cycle is dependent on …

Carbon monoxide (CO) is well-known as toxic gas and intrinsic signaling molecule such as
neurotransmitter and blood vessel relaxant. Recently, it has been reported that low …

The present study investigated whether there is an interaction between reactive oxygen
species (ROS) and p38 mitogen-activated protein kinase (MAPK) during chemical hypoxia …

We have previously shown that hypoxia results in increased activation of caspase-9 in the
cerebral cortex of newborn piglets. The present study tests the hypothesis that the increased …

Glioblastoma patients receive anti-inflammatory agent for alleviation of vasogenic edema
and pain prior to surgery, radiotherapy, and chemotherapy. Oxidative stress is an important …