Ambient air pollution exaggerates adipose inflammation and insulin resistance in a mouse model of diet-induced obesity
Q Sun, P Yue, JA Deiuliis, CN Lumeng, T Kampfrath… - Circulation, 2009 - Am Heart Assoc
Background—There is a strong link between urbanization and type 2 diabetes mellitus.
Although a multitude of mechanisms have been proposed, there are no studies evaluating …
Although a multitude of mechanisms have been proposed, there are no studies evaluating …
Exposure to fine particulate air pollution causes vascular insulin resistance by inducing pulmonary oxidative stress
P Haberzettl, TE O'Toole, A Bhatnagar… - Environmental health …, 2016 - ehp.niehs.nih.gov
Background: Epidemiological evidence suggests that exposure to ambient air fine
particulate matter (PM2. 5) increases the risk of developing type 2 diabetes and …
particulate matter (PM2. 5) increases the risk of developing type 2 diabetes and …
[HTML][HTML] Exposure to fine airborne particulate matter induces macrophage infiltration, unfolded protein response, and lipid deposition in white adipose tissue
Recent epidemiological studies have suggested a link between exposure to ambient air-
pollution and susceptibility to metabolic disorders such as Type II diabetes mellitus …
pollution and susceptibility to metabolic disorders such as Type II diabetes mellitus …
[HTML][HTML] Exaggerated effects of particulate matter air pollution in genetic type II diabetes mellitus
C Liu, Y Bai, X Xu, L Sun, A Wang, TY Wang… - Particle and fibre …, 2014 - Springer
Background Prior experimental and epidemiologic data support a link between exposure to
fine ambient particulate matter (< 2.5 μm in aerodynamic diameter, PM 2.5) and …
fine ambient particulate matter (< 2.5 μm in aerodynamic diameter, PM 2.5) and …
Ambient and traffic-related air pollution exposures as novel risk factors for metabolic dysfunction and type 2 diabetes
Abstract Purpose of Review Diabetes mellitus is a top contributor to the global burden of
mortality and disability in adults. There has also been a slow but steady rise in prediabetes …
mortality and disability in adults. There has also been a slow but steady rise in prediabetes …
Epidemiological and experimental links between air pollution and type 2 diabetes
C Liu, Z Ying, J Harkema, Q Sun… - Toxicologic …, 2013 - journals.sagepub.com
There is increasing evidence suggesting links between exposure to environmental toxins
and susceptibility to type 2 diabetes mellitus (DM). In this review, we summarize the …
and susceptibility to type 2 diabetes mellitus (DM). In this review, we summarize the …
Air pollution–mediated susceptibility to inflammation and insulin resistance: influence of CCR2 pathways in mice
C Liu, X Xu, Y Bai, TY Wang, X Rao… - Environmental …, 2014 - ehp.niehs.nih.gov
Background: Epidemiologic and experimental studies support an association between PM2.
5 exposure and insulin resistance (IR). Innate immune cell activation has been suggested to …
5 exposure and insulin resistance (IR). Innate immune cell activation has been suggested to …
Long-term exposure to ambient fine particulate pollution induces insulin resistance and mitochondrial alteration in adipose tissue
X Xu, C Liu, Z Xu, K Tzan, M Zhong… - Toxicological …, 2011 - academic.oup.com
We have previously shown that chronic exposure to ambient fine particulate matter (less
than 2.5 μm in aerodynamic diameter, PM2. 5) pollution in conjunction with high-fat diet …
than 2.5 μm in aerodynamic diameter, PM2. 5) pollution in conjunction with high-fat diet …
[HTML][HTML] Inflammatory response to fine particulate air pollution exposure: neutrophil versus monocyte
Objectives Studies have shown that chronic exposure to ambient fine particulate matter (less
than 2.5 µ m in aerodynamic diameter, PM2. 5) pollution induces insulin resistance through …
than 2.5 µ m in aerodynamic diameter, PM2. 5) pollution induces insulin resistance through …
[HTML][HTML] Ambient particulate air pollution induces oxidative stress and alterations of mitochondria and gene expression in brown and white adipose tissues
Z Xu, X Xu, M Zhong, IP Hotchkiss… - Particle and fibre …, 2011 - Springer
Background Prior studies have demonstrated a link between air pollution and metabolic
diseases such as type II diabetes. Changes in adipose tissue and its mitochondrial …
diseases such as type II diabetes. Changes in adipose tissue and its mitochondrial …
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