Increased Alzheimer's risk during the menopause transition: a 3-year longitudinal brain imaging study
Two thirds of all persons with late-onset Alzheimer's disease (AD) are women. Identification
of sex-based molecular mechanisms underpinning the female-based prevalence of AD …
of sex-based molecular mechanisms underpinning the female-based prevalence of AD …
Sex differences in Alzheimer risk: Brain imaging of endocrine vs chronologic aging
Objective: This observational multimodality brain imaging study investigates emergence of
endophenotypes of late-onset Alzheimer disease (AD) risk during endocrine transition states …
endophenotypes of late-onset Alzheimer disease (AD) risk during endocrine transition states …
Sex-driven modifiers of Alzheimer risk: a multimodality brain imaging study
Objective To investigate sex differences in late-onset Alzheimer disease (AD) risks by
means of multimodality brain biomarkers (β-amyloid load via 11C-Pittsburgh compound B …
means of multimodality brain biomarkers (β-amyloid load via 11C-Pittsburgh compound B …
Female sex and Alzheimer's risk: the menopause connection
O Scheyer, A Rahman, H Hristov, C Berkowitz… - The journal of …, 2018 - Springer
Along with advanced age and apolipoprotein E (APOE)-4 genotype, female sex is a major
risk factor for developing late-onset Alzheimer's disease (AD). Considering that AD …
risk factor for developing late-onset Alzheimer's disease (AD). Considering that AD …
[HTML][HTML] Sex and gender driven modifiers of Alzheimer's: the role for estrogenic control across age, race, medical, and lifestyle risks
A Rahman, H Jackson, H Hristov… - Frontiers in aging …, 2019 - frontiersin.org
Research indicates that after advanced age, the major risk factor for late-onset Alzheimer's
disease is female sex. Out of every three AD patients, two are females with postmenopausal …
disease is female sex. Out of every three AD patients, two are females with postmenopausal …
Female specific risk factors for the development of Alzheimer's disease neuropathology and cognitive impairment: Call for a precision medicine approach
C Udeh-Momoh, T Watermeyer - Ageing Research Reviews, 2021 - Elsevier
Alzheimer's disease (AD) includes a long asymptomatic stage, which precedes the formal
diagnosis of dementia. AD biomarker models provide a framework for precision medicine …
diagnosis of dementia. AD biomarker models provide a framework for precision medicine …
Sex differences in the association between AD biomarkers and cognitive decline
Women are disproportionately affected by Alzheimer's disease (AD) in terms of both disease
prevalence and severity. Previous autopsy work has suggested that, in the presence of AD …
prevalence and severity. Previous autopsy work has suggested that, in the presence of AD …
Menopause impacts human brain structure, connectivity, energy metabolism, and amyloid-beta deposition
All women undergo the menopause transition (MT), a neuro-endocrinological process that
impacts aging trajectories of multiple organ systems including brain. The MT occurs over …
impacts aging trajectories of multiple organ systems including brain. The MT occurs over …
Association of age at menopause and hormone therapy use with tau and β-amyloid positron emission tomography
Importance Postmenopausal females represent around 70% of all individuals with
Alzheimer disease. Previous literature shows elevated levels of tau in cognitively …
Alzheimer disease. Previous literature shows elevated levels of tau in cognitively …
Women's brain aging: Effects of sex‐hormone exposure, pregnancies, and genetic risk for Alzheimer's disease
Sex hormones such as estrogen fluctuate across the female lifespan, with high levels during
reproductive years and natural decline during the transition to menopause. Women's …
reproductive years and natural decline during the transition to menopause. Women's …