Trypanosoma cruzi is the causative agent of Chagas disease, the most important parasitic
infection in Latin America. Despite a global research effort, there have been no significant …

Chagas disease is caused by Trypanosoma cruzi, a protozoan parasite that displays
considerable genetic diversity. Infections result in a range of pathological outcomes, and …

The protozoan Trypanosoma cruzi is the causative agent of Chagas disease, one of the
world's major neglected infections. Although development of improved antiparasitic drugs is …

Chagas disease, caused by the intracellular protozoan Trypanosoma cruzi, affects 8–10
million people worldwide and represents a major public health challenge. There is no …

Background Chagas disease is caused by the protozoan parasite Trypanosoma cruzi and is
a serious public health problem throughout Latin America. With 6 million people infected …

Background The development of techniques that allow the imaging of animals infected with
parasites expressing luciferase opens up new possibilities for following the fate of parasites …

Background The long term and complex nature of Chagas disease in humans has restricted
studies on vaccine feasibility. Animal models also have limitations due to technical …

Chagas disease, caused by infection with the protozoan parasite Trypanosoma cruzi, is a
major public health problem in Central and South America. The pathogenesis of Chagas …

Infections with Trypanosoma cruzi are usually lifelong despite generating a strong adaptive
immune response. Identifying the sites of parasite persistence is therefore crucial to …

Investigations into intracellular replication and differentiation of Trypanosoma cruzi within
the mammalian host have been restricted by limitations in our ability to detect parasitized …