Beyond External Light: On-Spot Light Generation or Light Delivery for Highly Penetrated Photodynamic Therapy

X Cui, X Li, C Peng, Y Qiu, Y Shi, Y Liu, JF Fei - ACS nano, 2023 - ACS Publications
External light sources, such as lasers, light emitting diodes (LEDs) and lamps, are widely
applied in photodynamic therapy (PDT); however, their use is severely limited by the nature …

Photodynamic therapy of cancers with internal light sources: chemiluminescence, bioluminescence, and Cerenkov radiation

Y Zhang, Y Hao, S Chen, M Xu - Frontiers in Chemistry, 2020 - frontiersin.org
Photodynamic therapy (PDT) is a promising and minimally invasive modality for the
treatment of cancers. The use of a self-illuminating system as a light source provides an …

Internal Light Sources‐Mediated Photodynamic Therapy Nanoplatforms: Hope for the Resolution of the Traditional Penetration Problem

Y An, D Xu, X Wen, C Chen, G Liu… - Advanced healthcare …, 2024 - Wiley Online Library
Photodynamic therapy (PDT) is an alternative cancer treatment technique with a
noninvasive nature, high selectivity, and minimal adverse effects. The indispensable light …

Chemiluminescence and bioluminescence as an excitation source in the photodynamic therapy of cancer: a critical review

CM Magalhaes, JCG Esteves da Silva… - …, 2016 - Wiley Online Library
Photodynamic therapy (PDT) of cancer is known for its limited number of side effects, and
requires light, oxygen and photosensitizer. However, PDT is limited by poor penetration of …

All-natural-molecule, bioluminescent photodynamic therapy results in complete tumor regression and prevents metastasis

H Yan, S Forward, KH Kim, Y Wu, J Hui, A Kashiparekh… - Biomaterials, 2023 - Elsevier
Self-luminescent photodynamic therapy (PDT) has gained attention owing to its potential to
enable effective phototherapy without the bottleneck of shallow light penetration into tissues …

Recent advances in self-exciting photodynamic therapy

NT Blum, Y Zhang, J Qu, J Lin, P Huang - Frontiers in Bioengineering …, 2020 - frontiersin.org
Photodynamic therapy (PDT) is already (Food and Drug Administration) FDA approved and
used in the clinic for oncological treatment of pancreatic, lung, esophagus, bile duct, and of …

An implantable ultrasonically-powered micro-light-source (µlight) for photodynamic therapy

A Kim, J Zhou, S Samaddar, SH Song, BD Elzey… - Scientific reports, 2019 - nature.com
Photodynamic therapy (PDT) is a promising cancer treatment modality that can selectively
target unresectable tumors through optical activation of cytotoxic agents, thus reducing many …

Advanced techniques for performing photodynamic therapy in deep-seated tissues

B Sun, JNB Rahmat, Y Zhang - Biomaterials, 2022 - Elsevier
Photodynamic therapy (PDT) is a promising localized cancer treatment modality. It has been
used successfully to treat a range of dermatological conditions with comparable efficacy to …

[HTML][HTML] Recent advances in innovative strategies for enhanced cancer photodynamic therapy

T Hu, Z Wang, W Shen, R Liang, D Yan, M Wei - Theranostics, 2021 - ncbi.nlm.nih.gov
Photodynamic therapy (PDT), a non-invasive therapeutic modality, has received increasing
attention owing to its high selectivity and limited side effects. Although significant clinical …

Light-triggered photodynamic nanomedicines for overcoming localized therapeutic efficacy in cancer treatment

J Choi, IC Sun, HS Hwang, HY Yoon, K Kim - Advanced Drug Delivery …, 2022 - Elsevier
Photodynamic nanomedicines have significantly enhanced the therapeutic efficacy of
photosensitizers (PSs) by overcoming critical limitations of PSs such as poor water solubility …