HTLV-1 bZIP factor induces inflammation through labile Foxp3 expression

N Yamamoto-Taguchi, Y Satou, P Miyazato… - PLoS …, 2013 - journals.plos.org
Human T-cell leukemia virus type 1 (HTLV-1) causes both a neoplastic disease and
inflammatory diseases, including HTLV-1-associated myelopathy/tropical spastic …

HTLV-1 bZIP Factor Induces T-Cell Lymphoma and Systemic Inflammation In Vivo

Y Satou, J Yasunaga, T Zhao, M Yoshida… - PLoS …, 2011 - journals.plos.org
Human T-cell leukemia virus type 1 (HTLV-1) is the causal agent of a neoplastic disease of
CD4+ T cells, adult T-cell leukemia (ATL), and inflammatory diseases including HTLV-1 …

Interferon-γ promotes inflammation and development of T-cell lymphoma in HTLV-1 bZIP factor transgenic mice

Y Mitagami, J Yasunaga, H Kinosada… - PLoS …, 2015 - journals.plos.org
Human T-cell leukemia virus type 1 (HTLV-1) is an etiological agent of several inflammatory
diseases and a T-cell malignancy, adult T-cell leukemia (ATL). HTLV-1 bZIP factor (HBZ) is …

HTLV-1 bZIP factor impairs cell-mediated immunity by suppressing production of Th1 cytokines

K Sugata, Y Satou, J Yasunaga, H Hara… - Blood, The Journal …, 2012 - ashpublications.org
Adult T-cell leukemia (ATL) patients and human T-cell leukemia virus-1 (HTLV-1) infected
individuals succumb to opportunistic infections. Cell mediated immunity is impaired, yet the …

Reduced Foxp3 protein expression is associated with inflammatory disease during human t lymphotropic virus type 1 Infection

U Oh, C Grant, C Griffith, K Fugo… - The Journal of …, 2006 - academic.oup.com
The Foxp3 protein is a specific marker of CD4+ CD25+ regulatory T (Treg) cells, and its
expression is critical to their development and function. Several studies have demonstrated …

HTLV-1 modulates the frequency and phenotype of FoxP3+CD4+T cells in virus-infected individuals

Y Satou, A Utsunomiya, J Tanabe, M Nakagawa… - Retrovirology, 2012 - Springer
Abstract Background HTLV-1 utilizes CD4 T cells as the main host cell and maintains the
proviral load via clonal proliferation of infected CD4+ T cells. Infection of CD4+ T cells by …

HTLV-1 induces a Th1-like state in CD4+CCR4+ T cells

N Araya, T Sato, H Ando, U Tomaru… - The Journal of …, 2014 - Am Soc Clin Investig
Human T-lymphotropic virus type 1 (HTLV-1) is linked to multiple diseases, including the
neuroinflammatory disease HTLV-1–associated myelopathy/tropical spastic paraparesis …

HTLV-1 bZIP factor impairs anti-viral immunity by inducing co-inhibitory molecule, T cell immunoglobulin and ITIM domain (TIGIT)

K Yasuma, J Yasunaga, K Takemoto, K Sugata… - PLoS …, 2016 - journals.plos.org
Human T-cell leukemia virus type 1 (HTLV-1) infects CD4+ T cells and induces proliferation
of infected cells in vivo, which leads to the onset of adult T-cell leukemia (ATL) in some …

Human T-cell leukemia virus type 1 and Foxp3 expression: viral strategy in vivo

P Miyazato, M Matsuoka - International immunology, 2014 - academic.oup.com
Human T-cell leukemia virus type 1 and Foxp3 expression: viral strategy in vivo | International
Immunology | Oxford Academic Skip to Main Content Advertisement intended for healthcare …

HTLV-1 alters T cells for viral persistence and transmission

A Tanaka, M Matsuoka - Frontiers in microbiology, 2018 - frontiersin.org
Human T-cell leukemia virus type 1 (HTLV-1) was the first retrovirus to be discovered as a
causative agent of adult T-cell leukemia-lymphoma (ATL) and chronic inflammatory …