Inflammation after spinal cord injury: a review of the critical timeline of signaling cues and cellular infiltration
DJ Hellenbrand, CM Quinn, ZJ Piper… - Journal of …, 2021 - Springer
Traumatic spinal cord injury (SCI) is a devastating neurological condition that results in a
loss of motor and sensory function. Although extensive research to develop treatments for …
loss of motor and sensory function. Although extensive research to develop treatments for …
Inflammation: a target for treatment in spinal cord injury
X Freyermuth-Trujillo, JJ Segura-Uribe… - Cells, 2022 - mdpi.com
Spinal cord injury (SCI) is a significant cause of disability, and treatment alternatives that
generate beneficial outcomes and have no side effects are urgently needed. SCI may be …
generate beneficial outcomes and have no side effects are urgently needed. SCI may be …
Harmful and beneficial effects of inflammation after spinal cord injury: potential therapeutic implications
Spinal cord injury (SCI) results in immediate damage followed by a secondary phase of
tissue damage that occurs over a period of several weeks. The mechanisms underlying this …
tissue damage that occurs over a period of several weeks. The mechanisms underlying this …
Immune response following traumatic spinal cord injury: Pathophysiology and therapies
RC Sterner, RM Sterner - Frontiers in immunology, 2023 - frontiersin.org
Traumatic spinal cord injury (SCI) is a devastating condition that is often associated with
significant loss of function and/or permanent disability. The pathophysiology of SCI is …
significant loss of function and/or permanent disability. The pathophysiology of SCI is …
Inflammatory pathways in spinal cord injury
S David, JG Zarruk, N Ghasemlou - International review of neurobiology, 2012 - Elsevier
Injury to the spinal cord results in direct damage to axons, neuronal cell bodies, and glia that
cause functional loss below the site of injury. In addition, the injury also triggers an …
cause functional loss below the site of injury. In addition, the injury also triggers an …
The pathophysiological role of acute inflammation after spinal cord injury
S Okada - Inflammation and regeneration, 2016 - Springer
Traumatic spinal cord injury (SCI) causes irreparable severe motor and sensory dysfunction.
Mechanical trauma rapidly leads to blood-spinal cord barrier disruption, neural cell death …
Mechanical trauma rapidly leads to blood-spinal cord barrier disruption, neural cell death …
Multiple organ dysfunction and systemic inflammation after spinal cord injury: a complex relationship
X Sun, ZB Jones, X Chen, L Zhou, KF So… - Journal of …, 2016 - Springer
Spinal cord injury (SCI) is a devastating event that results in significant physical disabilities
for affected individuals. Apart from local injury within the spinal cord, SCI patients develop a …
for affected individuals. Apart from local injury within the spinal cord, SCI patients develop a …
Insights into the dual role of inflammation after spinal cord injury
Injuries to the CNS lead to severe and often irreversible deficits in sensorimotor and
autonomous function. In spinal cord injury (SCI), mechanical damage results in the death of …
autonomous function. In spinal cord injury (SCI), mechanical damage results in the death of …
Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury
DJ Donnelly, PG Popovich - Experimental neurology, 2008 - Elsevier
Trauma to the central nervous system (CNS) triggers intraparenchymal inflammation and
activation of systemic immunity with the capacity to exacerbate neuropathology and …
activation of systemic immunity with the capacity to exacerbate neuropathology and …
Quantitative analysis of cellular inflammation after traumatic spinal cord injury: evidence for a multiphasic inflammatory response in the acute to chronic environment
KD Beck, HX Nguyen, MD Galvan, DL Salazar… - Brain, 2010 - academic.oup.com
Traumatic injury to the central nervous system results in the disruption of the blood
brain/spinal barrier, followed by the invasion of cells and other components of the immune …
brain/spinal barrier, followed by the invasion of cells and other components of the immune …
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