Abstract introduction: The number of medications approved for AUD is small and they
generally have limited efficacy. We need new pharmacotherapies for the management of …

There is a critical need to increase the armamentarium of medications for AUD. Human
laboratory studies may help screen and prioritize promising targets and compounds before …

Alcohol use disorder (AUD) is a highly prevalent but severely under-treated disorder, with
only three widely-approved pharmacotherapies. Given that AUD is a very heterogeneous …

Alcohol use disorder (AUD), as currently defined in the Diagnostic and Statistical Manual,
5th Edition (DSM–5), is a heterogeneous disorder stemming from a complex interaction of …

Introduction: Only a few medications are available for the treatment of alcohol use disorders
(AUDs). Areas covered: This paper discusses approved AUD medications, including the …

Highlights•Alcoholism is a progressive disorder involving several neurotransmitter
systems.•Currently, there are only 3 approved medications.•Nalmefene is pending for …

Introduction: Alcohol use disorder (AUD) is a complex psychiatric condition characterized by
craving, compulsive seeking, loss of control of alcohol consumption as well as the …

Patients who suffer from alcohol use disorders (AUDs) usually go through various socio-
behavioral and pathophysiological changes that take place in the brain and other organs …

Chronic heavy alcohol use impacts all major neurotransmitter systems and is associated
with multiple medical, psychiatric, and social problems. Available evidence‐based …

More than 76 million people world‐wide are estimated to have diagnosable alcohol use
disorders (AUDs)(alcohol abuse or dependence), making these disorders a major global …