Biomarkers for dementia and mild cognitive impairment in Parkinson's disease

M Delgado‐Alvarado, B Gago… - Movement …, 2016 - Wiley Online Library
Cognitive decline is one of the most frequent and disabling nonmotor features of Parkinson's
disease. Around 30% of patients with Parkinson's disease experience mild cognitive …

Risk and incidence of dementia in a cohort of older subjects with Parkinson's disease in the United Kingdom

P Hobson, J Meara - Movement Disorders, 2004 - Wiley Online Library
To determine the incidence and possible risk factors for dementia in patients with clinically
probable Parkinson's disease (PD), a cohort (n= 86) of nondemented patients over 65 years …

Changes in motor subtype and risk for incident dementia in Parkinson's disease

G Alves, JP Larsen, M Emre… - … : official journal of the …, 2006 - Wiley Online Library
The objective of this study was to assess the temporal relationship between changes in
predominant motor symptoms and incident dementia in Parkinson's disease (PD). A …

Provisional diagnostic criteria for depression in Parkinson's disease: report of an NINDS/NIMH Work Group

L Marsh, WM McDonald, J Cummings… - Movement …, 2006 - Wiley Online Library
Mood disorders are the most common psychiatric problem associated with Parkinson's
disease (PD), and have a negative impact on disability and quality of life. Accurate diagnosis …

International validation of a behavioral scale in Parkinson's disease without dementia

I Rieu, P Martinez‐Martin, B Pereira… - Movement …, 2015 - Wiley Online Library
Abstract The “Ardouin Scale of Behavior in Parkinson's Disease” is a new instrument
specifically designed for assessing mood and behavior with a view to quantifying changes …

Comorbidity of the nonmotor symptoms of Parkinson's disease

LM Shulman, RL Taback, J Bean… - … : official journal of the …, 2001 - Wiley Online Library
Many patients with Parkinson's disease (PD) have clinically significant anxiety, depression,
fatigue, sleep disturbance, or sensory symptoms. The comorbidity of these nonmotor …

Nonmotor versus motor symptoms: how much do they matter to health status in Parkinson's disease?

C Hinnell, CS Hurt, S Landau, RG Brown… - Movement …, 2012 - Wiley Online Library
Evidence suggests that both motor and nonmotor symptoms contribute to health status in
Parkinson's disease. Less clear is how much change in health status can be expected if …

The Unified Parkinson's Disease Rating Scale: validation study of the mentation, behavior, and mood section

SE Starkstein, M Merello - Movement disorders: official journal …, 2007 - Wiley Online Library
The objective of this study was to examine the validity of the mentation, behavior, and mood
items included in Part I of the Unified Parkinson's Disease Rating Scale (UPDRS) and to …

A data‐driven approach to the study of heterogeneity in idiopathic Parkinson's disease: identification of three distinct subtypes

JM Graham, HJ Sagar - Movement disorders: official journal of …, 1999 - Wiley Online Library
Idiopathic Parkinson's disease (IPD) has been subclassified on the basis of predominant
motor symptomatology, age at disease onset, depressive affect, and cognitive performance …

Prevalence and clinical aspects of mild cognitive impairment in Parkinson's disease: A meta‐analysis

C Baiano, P Barone, L Trojano… - Movement …, 2020 - Wiley Online Library
Mild cognitive impairment associated with Parkinson's disease (PD) is a risk factor for the
development of dementia. Despite the importance of early identification of mild cognitive …