Inflammatory mediators and cytokines--new aspects of the pathophysiology and assessment of severity of acute pancreatitis?

V Gross, HG Leser, A Heinisch… - Hepato …, 1993 - europepmc.org
Most attacks of acute pancreatitis are mild and self-limiting. In 10-20% of the cases,
however, severe disease with multiple systemic complications develops. During the last few …

Inflammatory response in the early prediction of severity in human acute pancreatitis.

JA Viedma, M Perez-Mateo, J Agullo, JE Domínguez… - Gut, 1994 - gut.bmj.com
The role of the inflammatory response in acute pancreatitis and its relation with the clinical
course was examined. This study examined if the serial measurement of polymorphonuclear …

Cytokines and organ failure in acute pancreatitis: inflammatory response in acute pancreatitis

ML Malmstrøm, MB Hansen, AM Andersen, AK Ersbøll… - Pancreas, 2012 - journals.lww.com
Objectives We aimed at synchronously examining the early time course of 4 proinflammatory
cytokines as predictive factors for development of organ failure in patients with acute …

Interleukins in acute pancreatitis

J Schölmerich - Scandinavian Journal of Gastroenterology, 1996 - Taylor & Francis
Cytokines and their endogenous antagonists are released from inflammatory cells during
acute pancreatitis, in particular its severe form. They can be found early in the course of the …

Differential roles of inflammatory cells in pancreatitis

J Mayerle, A Dummer, M Sendler… - Journal of …, 2012 - Wiley Online Library
The incidence of acute pancreatitis per 100 000 of population ranges from 5 to 80. Patients
suffering from hemorrhagic‐necrotizing pancreatitis die in 10–24% of cases. 80% of all …

Pathophysiological mechanisms of acute pancreatitis define inflammatory markers of clinical prognosis

GA Minkov, KS Halacheva, YP Yovtchev… - Pancreas, 2015 - journals.lww.com
Abstract Development of acute pancreatitis illustrates the need to understand the basic
mechanisms of disease progression to drive the exploration of therapeutic options …

Inflammatory mediators in acute pancreatitis

M Bhatia, M Brady, S Shokuhi… - The Journal of …, 2000 - Wiley Online Library
Inflammatory mediators play a key role in acute pancreatitis and the resultant multiple organ
dysfunction syndrome, which is the primary cause of death in this condition. Recent studies …

Blood concentrations of polymorphonuclear leucocyte elastase and interleukin‐6 are indicators for the occurrence of multiple organ failures at the early stage of acute …

S IKEI, M OGAWA… - Journal of gastroenterology …, 1998 - Wiley Online Library
We studied potential indicators of severe acute pancreatitis by measuring the blood
concentrations of various cytokines, polymorphonuclear leucocyte elastase (PMN‐E), acute …

The role of cytokines in the pathogenesis of acute pancreatitis

J Norman - The American Journal of Surgery, 1998 - Elsevier
Background: The systemic manifestations of acute pancreatitis are responsible for the
majority of pancreatitis-associated morbidity and mortality and are now believed to be due to …

PMN-elastase in comparison with CRP, antiproteases, and LDH as indicators of necrosis in human acute pancreatitis

W Uhl, M Büchler, P Malfertheiner, M Martini… - Pancreas, 1991 - journals.lww.com
We analyzed the role of polymorphonuclear granulocytes (PMN)-elastase in predicting the
prognosis of patients with acute pancreatitis in comparison with C-reactive protein (CRP) …