Molecular Docking and Molecular Dynamic Investigations of Xanthone-Chalcone Derivatives against Epidermal Growth Factor Receptor for Preliminary Discovery of …
Epidermal growth factor receptor (EGFR) is found to be overexpressed in cancer cells as it
controls angiogenesis, cell signaling, and proliferation mechanisms. Therefore, EGFR has …
controls angiogenesis, cell signaling, and proliferation mechanisms. Therefore, EGFR has …
Molecular Docking Approach For Design and Synthesis of Thioxanthone Derivatives as Anticancer Agents
Thioxanthone derivatives were docked, synthesized, and tested for their anticancer activity.
The molecular docking results showed that 1‐hydroxythioxanthone, 2‐chloro‐1 …
The molecular docking results showed that 1‐hydroxythioxanthone, 2‐chloro‐1 …
Molecular docking studies and ADME predictions on synthesized chalcone compounds targeting EGFR
Ö Gündoğdu - Hittite Journal of Science and Engineering, 2023 - dergipark.org.tr
In the present study, new chalcone derivatives (5a–5f) obtained from the condensation
reaction of cuminaldehyde and acetophenone compounds containing different substituents …
reaction of cuminaldehyde and acetophenone compounds containing different substituents …
[HTML][HTML] Molecular docking based screening of novel designed chalcone series of compounds for their anti-cancer activity targeting EGFR kinase domain
Epidermal growth factor receptors (EGFR) are critical for the growth of many tumors and
expressed at high levels in about one third of epithelial cancers. Hence, blockade of the …
expressed at high levels in about one third of epithelial cancers. Hence, blockade of the …
Molecular Docking Analysis of Hydroxy Chalcones and Flavones from Anisaldehyde and Veratraldehyde as EGFR Inhibitors: Predicting Anticancer Potential
This study aimed to investigate the potential of hydroxy chalcone and flavone derivatives as
inhibitors of the epidermal growth factor receptor (EGFR) with anticancer properties …
inhibitors of the epidermal growth factor receptor (EGFR) with anticancer properties …
[PDF][PDF] Design of thioxanthone derivatives as potential tyrosine kinase inhibitor: A molecular docking study
Xanthone derivatives have been well-known for their wide and outstanding bioactivity so far.
However, investigation of thioxanthone derivatives and their biological activity is rarely …
However, investigation of thioxanthone derivatives and their biological activity is rarely …
Synthesis, Cytotoxicity Evaluation and Molecular Docking Studies of Xanthyl-Cinnamate Derivatives as Potential Anticancer Agents
MR Iresha, J Jumina, HD Pranowo… - Indonesian Journal of …, 2022 - journal.ugm.ac.id
A new series of xanthyl-cinnamate hybrid compounds (4a-d) have been synthesized and
screened through in vitro assay against four human cancer cell lines, ie, HeLa, T47D, A549 …
screened through in vitro assay against four human cancer cell lines, ie, HeLa, T47D, A549 …
[HTML][HTML] In-vitro cytotoxicity and in-silico investigation of the anticancer potential of 3-methoxyxanthen-9-one from Garcinia lanceifolia Roxb
MA Hossain, SK Mahato, MS Rana - Informatics in Medicine Unlocked, 2023 - Elsevier
For its beneficial effects on health, Garcinia lanceifolia Roxb. Has long been used as a
vegetable and in juice. In this study, as part of the process of finding and developing new …
vegetable and in juice. In this study, as part of the process of finding and developing new …
[HTML][HTML] Insights from molecular modeling, docking and simulation of imidazole nucleus containing chalcones with EGFR kinase domain for improved binding function
GE Rao, SA Rahaman, AP Rani - Bioinformation, 2016 - ncbi.nlm.nih.gov
EGFR Kinase domain is a crucial role player cell surface receptor protein activated by
specific binding of its ligand like EGFR. Importance of this protein as a therapeutically …
specific binding of its ligand like EGFR. Importance of this protein as a therapeutically …
In vitro and in silico studies of quercetin and daidzin as selective anticancer agents
Quercetin and daidzin are flavonoid and flavonoid glycoside type compounds that have
been found in many plants and nutraceuticals. This study aims to examine the in vitro …
been found in many plants and nutraceuticals. This study aims to examine the in vitro …
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