Cationic gold nanoparticles elicit mitochondrial dysfunction: A multi-omics study

A Gallud, K Klöditz, J Ytterberg, N Östberg… - Scientific reports, 2019 - nature.com
Abstract Systems biology is increasingly being applied in nanosafety research for observing
and predicting the biological perturbations inflicted by exposure to nanoparticles (NPs). In …

Differential cytotoxic effects of gold nanoparticles in different mammalian cell lines

PJ Chueh, RY Liang, YH Lee, ZM Zeng… - Journal of hazardous …, 2014 - Elsevier
Gold nanoparticles (AuNPs) possess unique properties that have been exploited in several
medical applications. However, a more comprehensive understanding of the environmental …

Gold nanoparticles of diameter 1.4 nm trigger necrosis by oxidative stress and mitochondrial damage

Y Pan, A Leifert, D Ruau, S Neuss, J Bornemann… - small, 2009 - Wiley Online Library
Gold nanoparticles (AuNPs) are generally considered nontoxic, similar to bulk gold, which is
inert and biocompatible. AuNPs of diameter 1.4 nm capped with triphenylphosphine …

Surface charge of gold nanoparticles mediates mechanism of toxicity

NM Schaeublin, LK Braydich-Stolle, AM Schrand… - Nanoscale, 2011 - pubs.rsc.org
Recently gold nanoparticles (Au NPs) have shown promising biological and military
applications due to their unique electronic and optical properties. However, little is known …

A combined proteomics and metabolomics approach to assess the effects of gold nanoparticles in vitro

S Gioria, J Lobo Vicente, P Barboro, R La Spina… - …, 2016 - Taylor & Francis
Omics technologies, such as proteomics or metabolomics, have to date been applied in the
field of nanomaterial safety assessment to a limited extent. To address this dearth, we …

Toxicity of citrate-capped AuNPs: an in vitro and in vivo assessment

S Sabella, V Brunetti, G Vecchio, A Galeone… - Journal of nanoparticle …, 2011 - Springer
In this study, we show that 15 nm citrate-capped AuNPs exert a remarkable toxicity in living
systems. The assessment was performed by using well-characterized AuNPs, the …

[HTML][HTML] A proteomic approach to investigate AuNPs effects in Balb/3T3 cells

S Gioria, H Chassaigne, D Carpi, A Parracino… - Toxicology letters, 2014 - Elsevier
Although gold nanoparticles (AuNPs) are currently used in several industrial products and
biomedical applications, information about their biological effects is very limited. Thus, it is …

Biogenic gold nanoparticles induce cell cycle arrest through oxidative stress and sensitize mitochondrial membranes in A549 lung cancer cells

V Ramalingam, S Revathidevi, T Shanmuganayagam… - RSC …, 2016 - pubs.rsc.org
The present study aims to find a facile, green and more yielding approach for the synthesis
of high stability gold nanoparticles (AuNPs) with a monodispersed nature using an aqueous …

[PDF][PDF] The toxicity of Gold Nanoparticles in relation to their physiochemical properties.

CS Yah - Biomedical Research (0970-938X), 2013 - researchgate.net
The rapid emergence of gold nanoparticles (AuNPs) technology holds great promise for
future applications due to their large volume specific surface areas with high diverse surface …

Histological injury to rat brain, liver, and kidneys by gold nanoparticles is dose-dependent

BS Fadia, N Mokhtari-Soulimane, B Meriem… - ACS …, 2022 - ACS Publications
Gold nanoparticles (GNPs) possess various interesting plasmonic properties that can
provide a variety of diagnostic and therapeutic functionalities for biomedical applications …