Clinical development and potential of photothermal and photodynamic therapies for cancer

X Li, JF Lovell, J Yoon, X Chen - Nature reviews Clinical oncology, 2020 - nature.com
Light-activated, photosensitizer-based therapies have been established as safe modalities
of tumour ablation for numerous cancer indications. Two main approaches are available …

A cascade fret photosensitizer that enhances photodynamic therapy for ocular melanoma

J Ruan, F Li, H Tian, J Yu, H Deng, S Ge, KW Leong - Nano Today, 2022 - Elsevier
Photodynamic therapy (PDT) relies on the generation of cytotoxic singlet oxygen (1 O 2)
from an otherwise nontoxic photosensitizer accumulated in tumor tissue to treat cancer …

[HTML][HTML] Progress in clinical trials of photodynamic therapy for solid tumors and the role of nanomedicine

HO Alsaab, MS Alghamdi, AS Alotaibi, R Alzhrani… - Cancers, 2020 - mdpi.com
Simple Summary Photodynamic therapy (PDT) has been undertaken with growing focus in
recent studies to identify successful anticancer therapies. The field of PDT has evolved …

Optical imaging, photodynamic therapy and optically triggered combination treatments

S Mallidi, BQ Spring, S Chang, B Vakoc… - The Cancer …, 2015 - journals.lww.com
Optical imaging is becoming increasingly promising for real-time image-guided resections,
and combined with photodynamic therapy (PDT), a photochemistry-based treatment …

[HTML][HTML] Development of Biotechnological Photosensitizers for Photodynamic Therapy: Cancer Research and Treatment—From Benchtop to Clinical Practice

M Aires-Fernandes, R Botelho Costa… - Molecules, 2022 - mdpi.com
Photodynamic therapy (PDT) is a noninvasive therapeutic approach that has been applied
in studies for the treatment of various diseases. In this context, PDT has been suggested as …

[HTML][HTML] Recent advances in strategies for addressing hypoxia in tumor photodynamic therapy

L Hong, J Li, Y Luo, T Guo, C Zhang, S Ou, Y Long… - Biomolecules, 2022 - mdpi.com
Photodynamic therapy (PDT) is a treatment modality that uses light to target tumors and
minimize damage to normal tissues. It offers advantages including high spatiotemporal …

[HTML][HTML] Near-infrared photoresponsive drug delivery nanosystems for cancer photo-chemotherapy

X Wang, Z Xuan, X Zhu, H Sun, J Li, Z Xie - Journal of nanobiotechnology, 2020 - Springer
Drug delivery systems (DDSs) based on nanomaterials have shown a promise for cancer
chemotherapy; however, it remains a great challenge to localize on-demand release of …

Enhanced photodynamic therapy for overcoming tumor hypoxia: From microenvironment regulation to photosensitizer innovation

J Du, T Shi, S Long, P Chen, W Sun, J Fan… - Coordination Chemistry …, 2021 - Elsevier
Photodynamic therapy (PDT) has garnered an increasing interest by both researchers and
clinicians as a non-invasive therapy that allows a selective treatment towards tumors …

Smart nanoreactors for pH-responsive tumor homing, mitochondria-targeting, and enhanced photodynamic-immunotherapy of cancer

G Yang, L Xu, J Xu, R Zhang, G Song, Y Chao… - Nano …, 2018 - ACS Publications
Photodynamic therapy (PDT) is an oxygen-dependent light-triggered noninvasive
therapeutic method showing many promising aspects in cancer treatment. For effective PDT …

[HTML][HTML] Utilisation of targeted nanoparticle photosensitiser drug delivery systems for the enhancement of photodynamic therapy

CA Kruger, H Abrahamse - Molecules, 2018 - mdpi.com
The cancer incidence world-wide has caused an increase in the demand for effective forms
of treatment. One unconventional form of treatment for cancer is photodynamic therapy …