Methods.: Healthy adult mice were exposed to an overpressure blast wave using a custom-
built blast chamber. The effects of blast exposure on retina and optic nerve function and …

Methods: Adult C57Bl/6 mice were exposed to a blast directed at one eye. Optical
coherence tomography and histology were performed to assess retina and optic nerve …

We developed and characterized a mouse model of primary ocular blast injury. The device
consists of: a pressurized air tank attached to a regulated paintball gun with a machined …

Traumatic brain injury due to blast exposure is currently the most prevalent of war injuries.
Although secondary ocular blast injuries due to flying debris are more common, primary …

Acoustic blast overpressure (ABO) injury in military personnel and civilians is often
accompanied by delayed visual deficits. However, most animal model studies dealing with …

Background Visual prognosis after an open globe injury is typically worse than after a closed
globe injury due, in part, to the immune response that ensues following open globe trauma …

Blast has been the leading cause of injury, particularly traumatic brain injury and visual
system injury, in combat operations in Iraq and Afghanistan. We determined the effect of …

Purpose: The purpose of this study was to examine the effect of multiple blast exposures and
blast preconditioning on the structure and function of retinal ganglion cells (RGCs), to …

Damage to the eye from blast exposure can occur as a result of the overpressure air-wave
(primary injury), flying debris (secondary injury), blunt force trauma (tertiary injury), and/or …

Purpose.: We qualitatively describe the anatomic features of primary blast ocular injury
observed using a postmortem porcine eye model. Porcine eyes were exposed to various …