Eslicarbazepine acetate: an update on efficacy and safety in epilepsy

A Verrotti, G Loiacono, A Rossi, G Zaccara - Epilepsy research, 2014 - Elsevier
Epilepsy is a common neurological disorder. Despite a broad range of commonly used
antiepileptic drugs, approximately 30% of patients with epilepsy have drug resistance or …

Eslicarbazepine acetate: a new improvement on a classic drug family for the treatment of partial-onset seizures

GL Galiana, AC Gauthier, RH Mattson - Drugs in R&D, 2017 - Springer
Eslicarbazepine acetate is a new anti-epileptic drug belonging to the dibenzazepine
carboxamide family that is currently approved as adjunctive therapy and monotherapy for …

Eslicarbazepine acetate: a new option for the treatment of focal epilepsy

J Ferreira, T Mestre - Expert opinion on investigational drugs, 2009 - Taylor & Francis
Background: Epilepsy is a neurological condition with an increased probability of seizure
occurrence through time. Although many anti-epileptic drugs (AEDs) exist, they fail to treat …

Eslicarbazepine acetate: its effectiveness as adjunctive therapy in clinical trials and open studies

SD Shorvon, E Trinka, BJ Steinhoff, M Holtkamp… - Journal of …, 2017 - Springer
Eslicarbazepine acetate (ESL) is a once-daily antiepileptic drug that is approved as
adjunctive therapy in adults with focal-onset seizures. Following oral administration, ESL is …

Eslicarbazepine acetate in the treatment of adults with partial-onset epilepsy: an evidence-based review of efficacy, safety and place in therapy

S Lattanzi, F Brigo, C Cagnetti, A Verrotti… - Core …, 2018 - Taylor & Francis
Introduction: Up to 30% of the patients diagnosed with epilepsy will continue suffering from
seizures despite treatment with antiepileptic drugs, either in monotherapy or polytherapy …

Pharmacokinetic/pharmacodynamic evaluation of eslicarbazepine for the treatment of epilepsy

M Banach, KK Borowicz… - Expert Opinion on Drug …, 2015 - Taylor & Francis
Introduction: Eslicarbazepine acetate (ESL) is a novel antiepileptic drug registered as the
adjunctive treatment of partial-onset seizures in adults. As a third-generation medication …

Clinical utility of eslicarbazepine: current evidence

G Zaccara, F Giovannelli, M Cincotta… - Drug design …, 2015 - Taylor & Francis
Eslicarbazepine acetate (ESL) is a new antiepileptic drug whose mechanism of action is
blockade of the voltage-gated sodium channel (VGSC). However, in respect to …

Update on treatment of partial onset epilepsy: role of eslicarbazepine

M Rauchenzauner, G Luef - Neuropsychiatric disease and …, 2010 - Taylor & Francis
Partial epilepsy comprises simple partial seizures, complex partial seizures, and secondarily
generalized seizures, and covers more than 60% of patients with epilepsy. Antiepileptic …

Eslicarbazepine acetate in epilepsies with focal and secondary generalised seizures: systematic review of current evidence

LM Willems, JP Zöllner, E Paule… - Expert review of …, 2018 - Taylor & Francis
Introduction: Eslicarbazepine acetate (ESL) is a third-generation antiepileptic drug (AED)
approved for adjunctive treatment in adults, children, and adolescents with focal-onset …

Eslicarbazepine acetate monotherapy: a review in partial-onset seizures

M Shirley, S Dhillon - Drugs, 2016 - Springer
Eslicarbazepine acetate (Aptiom®) is a once-daily, orally administered antiepileptic drug
(AED) approved previously in the EU, USA and several other countries for use as adjunctive …