[HTML][HTML] Strain wars 2: Binding constants, enthalpies, entropies, Gibbs energies and rates of binding of SARS-CoV-2 variants

M Popovic - Virology, 2022 - Elsevier
SARS-CoV-2 virus is the cause of COVID-19 pandemic and belongs to RNA viruses,
showing great tendency to mutate. Several dozens of mutations have been observed on the …

Strain Wars: Competitive interactions between SARS-CoV-2 strains are explained by Gibbs energy of antigen-receptor binding

M Popovic, M Popovic - Microbial risk analysis, 2022 - Elsevier
Since the beginning of the COVID-19 pandemic, SARS-CoV-2 has mutated several times
into new strains, with an increased infectivity. Infectivity of SARS-CoV-2 strains depends on …

[HTML][HTML] Binding affinity and mechanisms of SARS-CoV-2 variants

Y Han, Z Wang, Z Wei, I Schapiro, J Li - Computational and structural …, 2021 - Elsevier
During the rapid worldwide spread of SARS-CoV-2, the viral genome has been undergoing
numerous mutations, especially in the spike (S) glycoprotein gene that encode a type-I …

Strain wars 3: Differences in infectivity and pathogenicity between Delta and Omicron strains of SARS-CoV-2 can be explained by thermodynamic and kinetic …

M Popovic - Microbial risk analysis, 2022 - Elsevier
In this paper, for the first time, empirical formulas have been reported of the Delta and
Omicron strains of SARS-CoV-2. The empirical formula of the Delta strain entire virion was …

[HTML][HTML] Strain Wars 4-Darwinian evolution through Gibbs' glasses: Gibbs energies of binding and growth explain evolution of SARS-CoV-2 from Hu-1 to BA. 2

M Popovic - Virology, 2022 - Elsevier
All processes in nature are driven by negative Gibbs energy. Gibbs energy is used by
various viruses and their strains to hijack host cell metabolic machinery. The analysis was …

Never ending story? Evolution of SARS-CoV-2 monitored through Gibbs energies of biosynthesis and antigen-receptor binding of Omicron BQ. 1, BQ. 1.1, XBB and …

M Popovic - Microbial risk analysis, 2023 - Elsevier
RNA viruses exhibit a great tendency to mutate. Mutations occur in the parts of the genome
that encode the spike glycoprotein and less often in the rest of the genome. This is why …

The SARS-CoV-2 Hydra, a tiny monster from the 21st century: Thermodynamics of the BA. 5.2 and BF. 7 variants

M Popovic - Microbial Risk Analysis, 2023 - Elsevier
SARS-CoV-2 resembles the ancient mythical creature Hydra. Just like with the Hydra, when
one head is cut, it is followed by appearance of two more heads, suppression of one SARS …

Strain Wars 5: Gibbs energies of binding of BA. 1 through BA. 4 variants of SARS-CoV-2

M Popovic - Microbial risk analysis, 2022 - Elsevier
This paper reports, for the first time, standard Gibbs energies of binding of the BA. 1, BA. 2,
BA. 3, BA. 2.13, BA. 2.12. 1 and BA. 4 Omicron variants of SARS-CoV-2, to the Human ACE2 …

Upcoming epidemic storm: Empirical formulas, biosynthesis reactions, thermodynamic properties and driving forces of multiplication of the omicron XBB. 1.9. 1, XBF …

ME Popovic, M Mihailović, S Panić - Microbial Risk Analysis, 2023 - Elsevier
Abstract COVID-19 and SARS-CoV-2 from the perspectives of medicine, biology, molecular
biology, chemistry and biothermodynamics represent probably the best studied virus-host …

[HTML][HTML] Emerging mutations in envelope protein of SARS-CoV-2 and their effect on thermodynamic properties

K Mou, M Abdalla, DQ Wei, MT Khan, MS Lodhi… - Informatics in medicine …, 2021 - Elsevier
Structural proteins of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are
potential drug targets due to their role in the virus life cycle. The envelope (E) protein is one …