Outcome in treatment of childhood cancers has improved dramatically since the 1970s. This
success was largely achieved by the implementation of cooperative clinical research trial …

Every year, approximately 400 00 children worldwide are diagnosed with cancer. Although
treatment results in most types of childhood neoplasms are excellent with survival more than …

Survival of children with cancers has dramatically improved over the past several decades.
This success has been achieved through improvement of combined modalities in treatment …

This Special Series issue ofJournal of Clinical Oncologyhighlights collaborative efforts that
have contributed to the remarkable progress achieved in advancing survival for pediatric …

The translation of genomic discoveries to the clinic in pediatric oncology continues to move
forward at a brisk pace. Early adoption of genomics for tumor classification, risk stratification …

Four out of five children diagnosed with cancer can be cured with contemporary cancer
therapy. This represents a dramatic improvement since 50 years ago when the cure rate of …

Improvements in protocol-driven clinical trials and supportive care for children and
adolescents with cancer have reduced mortality rates by more than 50% over the past three …

Despite huge advances in the diagnosis and treatment of pediatric cancers over the past
several decades, it remains one of the leading causes of death during childhood in …

Precision oncologic medicine is an emerging approach for cancer treatment that has
recently taken giant steps in solid clinical practice. Recent advances in molecular …

The primary results of the first round of pediatric precision oncology clinical trials will provide
us with a greater understanding of the clinical impact of linking tumor profiling to selection of …