Does hypothermic machine perfusion of human donor livers affect risks of sinusoidal endothelial injury and microbial infection? A feasibility study assessing flow …

A Jomaa, K Gurusamy, PN Siriwardana… - Transplantation …, 2013 - Elsevier
BACKGROUND: Hypothermic machine perfusion (HMP) is better than conventional cold
storage in kidney transplantation. Large animal models suggest that HMP may be beneficial …

Hypothermic machine preservation attenuates ischemia/reperfusion markers after liver transplantation: preliminary results

JV Guarrera, SD Henry, SWC Chen, T Brown… - Journal of Surgical …, 2011 - Elsevier
BACKGROUND: Hypothermic machine perfusion (HMP) has shown significant benefits in
renal transplantation but is still in its infancy in liver transplantation. Potential benefits …

Ex-vivo study of flow dynamics and endothelial cell structure during extended hypothermic machine perfusion preservation of livers

S Jain, H Xu, H Duncan, JW Jones Jr, JX Zhang… - Cryobiology, 2004 - Elsevier
Liver transplantation is often the only effective treatment for end stage liver diseases
resulting from cirrhosis, hepatitis, progressive jaundice, and biliary atresia. Hypothermic …

Hypothermic machine perfusion of the liver: is it more complex than for the kidney?

D Monbaliu, V Heedfeld, Q Liu, T Wylin… - Transplantation …, 2011 - Elsevier
BACKGROUND: Hypothermic machine perfusion (HMP) is superior to simple cold storage
(SCS) for the preservation of kidney grafts. Whether HMP is superior to SCS for liver …

Hypothermic machine perfusion of the liver and the critical balance between perfusion pressures and endothelial injury

A van der Plaats, HGD Leuvenink, H van Goor… - Transplantation …, 2005 - Elsevier
Hypothermic machine perfusion (HMP) provides better protection against cold ischemic
injury than cold storage in marginal donor kidneys. Also, in liver transplantation a switch …

[HTML][HTML] Hypothermic machine preservation in human liver transplantation: the first clinical series

JV Guarrera, SD Henry, B Samstein… - American Journal of …, 2010 - Elsevier
Hypothermic machine perfusion (HMP) is widely used to preserve kidneys for
transplantation with improved results over cold storage (CS). To date, successful …

Pronlonged hypothermic machine perfusion preserves hepatocellular function but potentiates endothelial cell dysfunction in rat livers

H Xu, CY Lee, MG Clemens, JX Zhang - Transplantation, 2004 - journals.lww.com
Background. Although hypothermic machine perfusion (HMP) preservation has been shown
to improve organ function and to expand the organ donor pool, problems still exist with the …

Hypothermic machine perfusion of liver grafts for transplantation: technical development in human discard and miniature swine models

JV Guarrera, J Estevez, J Boykin, R Boyce… - Transplantation …, 2005 - Elsevier
INTRODUCTION: Cold storage (CS) is the standard preservation technique for liver
transplantation (LTx). Hypothermic machine perfusion (HMP) is an alternative preservation …

Influence of flow and addition of oxygen during porcine liver hypothermic machine perfusion

K Vekemans, Q Liu, J Brassil, M Komuta… - Transplantation …, 2007 - Elsevier
INTRODUCTION: In contrast with kidneys, data on hypothermic machine perfusion (HMP) of
livers remain scarce. Optimal liver HMP is poorly defined. Superiority of liver HMP over …

HETEROGENEOUS FLOW PATTERNS DURING HYPOTHERMIC MACHINE PERFUSION PRESERVATION OF LIVERS1

CY Lee, JX Zhang, H DeSilva, RN Coger… - …, 2000 - journals.lww.com
Background. Hypothermic machine perfusion preservation (MPP) has the potential to relieve
the current donor shortage problem by providing superior preserved tissue and viable non …