Chronic hypotensive effects of losartan are not dependent on the actions of angiotensin II at AT 2 receptors
JP Collister, SL Soucheray… - Journal of cardiovascular …, 2002 - journals.lww.com
We have previously demonstrated the chronic hypotensive effects of the AT 1 antagonist,
losartan, in normotensive, salt-replete rats. One explanation for this response is a reduction …
losartan, in normotensive, salt-replete rats. One explanation for this response is a reduction …
Hypotensive response to losartan in normal rats: role of Ang II and the area postrema
JP Collister, BJ Hornfeldt, JW Osborn - Hypertension, 1996 - Am Heart Assoc
We have reported that the angiotensin II (Ang II) AT1 receptor antagonist losartan markedly
lowers arterial pressure in sodium-replete, normotensive rats. We hypothesized that this …
lowers arterial pressure in sodium-replete, normotensive rats. We hypothesized that this …
Role of the angiotensin II AT2-subtype receptors in the blood pressure-lowering effect of losartan in salt-restricted rats
B Gigante, O Piras, P De Paolis, A Porcellini… - Journal of …, 1998 - journals.lww.com
Objective The aim of this study was to evaluate the potential role of the angiotensin II (Ang II)
AT 2 receptors (AT 2) in the control of blood pressure (BP) in the rat and the effects of AT 2 …
AT 2 receptors (AT 2) in the control of blood pressure (BP) in the rat and the effects of AT 2 …
Acute myocardial and vascular responses to specific angiotensin II antagonism in the spontaneously hypertensive rat
RJ Cody, PF Binkley, GJ Haas… - American journal of …, 1995 - academic.oup.com
As the AT1 receptor is the primary angiotensin II receptor in the myocardium and
vasculature, we assessed the acute myocardial and vascular response to the AT1 …
vasculature, we assessed the acute myocardial and vascular response to the AT1 …
Peripheral administration of AT1 receptor blockers and pressor responses to central angiotensin II and sodium
J Zhang, FHH Leenen - Canadian journal of physiology and …, 2001 - cdnsciencepub.com
Central administration of AT1 receptor blockers prevents salt-sensitive hypertension and
inhibits progression of CHF. We investigated in Wistar rats the effectiveness of peripheral …
inhibits progression of CHF. We investigated in Wistar rats the effectiveness of peripheral …
Effects of losartan on angiotensin and bradykinin peptides and angiotensin-converting enzyme
DJ Campbell, A Kladis, AJ Valentijn - Journal of cardiovascular …, 1995 - journals.lww.com
Antagonists of the type 1 (AT 1) angiotensin II (Ang II) receptor increase renin secretion and
plasma Ang II levels, and the increased Ang II levels may counteract the effects of the …
plasma Ang II levels, and the increased Ang II levels may counteract the effects of the …
Renal responses to AT1 blockade in angiotensin II-induced hypertensive rats.
CT Wang, LX Zou, LG Navar - Journal of the American Society of …, 1997 - journals.lww.com
Previous studies have shown that uninephrectomized rats infused chronically with low
doses of angiotensin II (Ang II) develop progressive hypertension that is prevented by …
doses of angiotensin II (Ang II) develop progressive hypertension that is prevented by …
[PDF][PDF] Time course of losartan blockade of angiotensin II hypertension versus blockade of angiotensin II fast pressor effects.
VJ Gorbea-Oppliger, MG Melaragno, GS Potter… - … of Pharmacology and …, 1994 - Citeseer
This study investigated the ability of the selective angiotensin II (All)-type (AT) 1 receptor
antagonist losartan to reverse the fast (< 30 sec) pressor effect of All, and the hypertension …
antagonist losartan to reverse the fast (< 30 sec) pressor effect of All, and the hypertension …
Effects of candesartan and PD123319 on responses to angiotensin II in the anesthetized mouse.
TJ Bivalacqua, A Dalal, DG Lambert… - Journal of the …, 1999 - europepmc.org
The effects of candesartan (30 microg/kg iv) and PD123319 (10 mg/kg iv) on changes in
systemic arterial pressure in response to angiotensin II (AngII) were investigated in the …
systemic arterial pressure in response to angiotensin II (AngII) were investigated in the …
Hemodynamic and Biochemical Effects of the AT1 Receptor Antagonist Irbesartan in Hypertension
AH van den Meiracker, PJJ Admiraal, JA Janssen… - …, 1995 - Am Heart Assoc
We studied the hemodynamic, neurohumoral, and biochemical effects of the novel
angiotensin type 1 (AT1) receptor antagonist irbesartan in 86 untreated patients with …
angiotensin type 1 (AT1) receptor antagonist irbesartan in 86 untreated patients with …