We have previously demonstrated the chronic hypotensive effects of the AT 1 antagonist,
losartan, in normotensive, salt-replete rats. One explanation for this response is a reduction …

We have reported that the angiotensin II (Ang II) AT1 receptor antagonist losartan markedly
lowers arterial pressure in sodium-replete, normotensive rats. We hypothesized that this …

Objective The aim of this study was to evaluate the potential role of the angiotensin II (Ang II)
AT 2 receptors (AT 2) in the control of blood pressure (BP) in the rat and the effects of AT 2 …

As the AT1 receptor is the primary angiotensin II receptor in the myocardium and
vasculature, we assessed the acute myocardial and vascular response to the AT1 …

Central administration of AT1 receptor blockers prevents salt-sensitive hypertension and
inhibits progression of CHF. We investigated in Wistar rats the effectiveness of peripheral …

Antagonists of the type 1 (AT 1) angiotensin II (Ang II) receptor increase renin secretion and
plasma Ang II levels, and the increased Ang II levels may counteract the effects of the …

Previous studies have shown that uninephrectomized rats infused chronically with low
doses of angiotensin II (Ang II) develop progressive hypertension that is prevented by …

This study investigated the ability of the selective angiotensin II (All)-type (AT) 1 receptor
antagonist losartan to reverse the fast (< 30 sec) pressor effect of All, and the hypertension …

The effects of candesartan (30 microg/kg iv) and PD123319 (10 mg/kg iv) on changes in
systemic arterial pressure in response to angiotensin II (AngII) were investigated in the …

We studied the hemodynamic, neurohumoral, and biochemical effects of the novel
angiotensin type 1 (AT1) receptor antagonist irbesartan in 86 untreated patients with …