Redox reactions control fundamental processes of human biology. Therefore, it is safe to
assume that the responses and adaptations to exercise are, at least in part, mediated by …

The central aim of this review is to address the highly multidisciplinary topic of redox biology
as related to exercise using an integrative and comparative approach rather than focusing …

Recent research highlights the importance of redox signalling pathway activation by
contraction-induced reactive oxygen species (ROS) and nitric oxide (NO) in normal exercise …

Exercise imposes cellular stress on contracting skeletal muscle fibers, forcing them to
complete molecular adaptations to maintain homeostasis. There is mounting evidence that …

The equivocal role of reactive species and redox signaling in exercise responses and
adaptations is an example clearly showing the inadequacy of current redox biology research …

Research in redox biology of exercise has made considerable advances in the last 70 years.
Since the seminal study of George Pake's group calculating the content of free radicals in …

In this review, we discuss exercise as an oxidative stressor, and elucidate the mechanisms
and downstream consequences of exercise-induced oxidative stress. Reactive oxygen …

Exercise redox biochemistry is of considerable interest owing to its translational value in
health and disease. However, unaddressed conceptual, methodological and technical …

Significance: Exercise-induced reactive oxygen species (ROS) production activates multiple
intracellular signaling pathways through genomic and nongenomic mechanisms that are …

Skeletal muscle contraction is associated with the production of ROS due to altered O2
distribution and flux in the cell. Despite a highly efficient antioxidant defense, a small surplus …