Plasma and urinary digoxin in thyroid dysfunction

GM Shenfield, J Thompson, DB Horn - European Journal of Clinical …, 1977 - Springer
The response to a single oral dose of 0.5 mg digoxin has been studied in eight patients, of
whom four were hyperthyroid and four were hypothyroid, both before and after treatment for …

Digoxin kinetics in patients with thyroid dysfunction

JR Lawrence, DJ Sumner, WJ Kalk… - Clinical …, 1977 - Wiley Online Library
The disposition of intravenously administered (3H)‐digoxin has been studied in 9
hyperthyroid and 4 hypothyroid patients. In 9 of these subjects the handling of …

The pharmacokinetics of digoxin in patients with manifest hyperthyroidism and after normalization of thyroid function.

J Bonelli, H Haydl, K Hruby, G Kaik - International Journal of Clinical …, 1978 - europepmc.org
The pharmakokinetic data (elimination half-life, apparent distribution volume, total and renal
clearance and cumulative urine excretion) were determined after intravenous administration …

Clinical pharmacokinetics of digoxin 1980

JK Aronson - Clinical pharmacokinetics, 1980 - Springer
The following summarises the contents of both this review and its predecessor in this journal
(Iisalo, 1977). The two reviews should be read in conjunction with each other. Digoxin is …

Evaluation of digoxin bioavailability in single-dose studies

DJ Greenblatt, DW Duhme… - New England Journal …, 1973 - Mass Medical Soc
Methods for testing digoxin bioavailability were compared in single-dose crossover studies
using eight healthy male subjects. Digoxin (0.75 mg) was given by intravenous infusion …

Serum digoxin values following a dosage regimen based on body weight, sex, age and renal function

NJB Christiansen, K Kølendorf… - Acta medica …, 1973 - Wiley Online Library
Serum digoxin has been determined by a radio‐immunological method in 99 patients
treated with digoxin. Digoxin was administered using a dosage regimen with a daily …

A comparison of the bioavailability of digoxin in capsule, tablet, and solution taken orally with intravenous digoxin.

PF Binnion - Journal of Clinical Pharmacology, 1976 - europepmc.org
Six healthy volunteers were given five single-dose treatments of 0.40 mg digoxin either
intravenously, in liquid form, in conventional tablet form (dissolution rate 76 per cent in 1 …

Excretion of digoxin and its metabolites in urine after a single oral dose in healthy subjects

JO Magnusson, B Bergdahl, C Bogentoft… - … & Drug Disposition, 1982 - Wiley Online Library
The 3‐day urinary excretion of digoxin, its conjugated and unconjugated hydrolytic
metabolites and dihydrodigoxin, was studied in 8 healthy men after oral administration of …

Absorption of digoxin from different oral preparations in normal subjects during steady state

DH Huffman, CV Manion… - Clinical Pharmacology & …, 1974 - Wiley Online Library
Digoxin bioavailability was studied in 6 normal volunteers during chronic dosing. The
absorption of digoxin was estimated by:(1) steady‐state serum dtgoxin levels;(2) the area …

The measurement of plasma digoxin concentration: A comparison of two methods

S Lader, A Bye, P Marsden - European Journal of Clinical Pharmacology, 1972 - Springer
No significant differences were found between plasma digoxin concentrations in samples
assayed by both radioimmunoassay and 86 Rb uptake. The mean plasma digoxin …