Etiology, pathogenesis and prevention of neural tube defects
R Padmanabhan - Congenital anomalies, 2006 - Wiley Online Library
Spina bifida, anencephaly, and encephalocele are commonly grouped together and termed
neural tube defects (NTD). Failure of closure of the neural tube during development results …
neural tube defects (NTD). Failure of closure of the neural tube during development results …
Investigations into the etiology of neural tube defects
RM Cabrera, DS Hill, AJ Etheredge… - Birth Defects Research …, 2004 - Wiley Online Library
Neural tube defects (NTDs) are serious malformations affecting approximately 1 per 1000
births, yet the mechanisms by which they arise are unknown. There have been consistent …
births, yet the mechanisms by which they arise are unknown. There have been consistent …
Insights into the etiology of mammalian neural tube closure defects from developmental, genetic and evolutionary studies
DM Juriloff, MJ Harris - Journal of developmental biology, 2018 - mdpi.com
The human neural tube defects (NTD), anencephaly, spina bifida and craniorachischisis,
originate from a failure of the embryonic neural tube to close. Human NTD are relatively …
originate from a failure of the embryonic neural tube to close. Human NTD are relatively …
Mouse mutants with neural tube closure defects and their role in understanding human neural tube defects
MJ Harris, DM Juriloff - Birth Defects Research Part A: Clinical …, 2007 - Wiley Online Library
BACKGROUND: The number of mouse mutants and strains with neural tube closure defects
(NTDs) now exceeds 190, including 155 involving known genes, 33 with unidentified genes …
(NTDs) now exceeds 190, including 155 involving known genes, 33 with unidentified genes …
An update to the list of mouse mutants with neural tube closure defects and advances toward a complete genetic perspective of neural tube closure
MJ Harris, DM Juriloff - Birth Defects Research Part A: Clinical …, 2010 - Wiley Online Library
The number of mouse mutants and strains with neural tube defects (NTDs) now exceeds
240, including 205 representing specific genes, 30 for unidentified genes, and 9 …
240, including 205 representing specific genes, 30 for unidentified genes, and 9 …
Neural tube defects, folic acid and methylation
A Imbard, JF Benoist, HJ Blom - International journal of environmental …, 2013 - mdpi.com
Neural tube defects (NTDs) are common complex congenital malformations resulting from
failure of the neural tube closure during embryogenesis. It is established that folic acid …
failure of the neural tube closure during embryogenesis. It is established that folic acid …
Epidemiology of neural tube defects
LE Mitchell - American journal of medical genetics Part C …, 2005 - Wiley Online Library
The epidemiological investigation of the common open neural tube defects (NTDs),
anencephaly, and spina bifida, has a long history. The most significant finding from these …
anencephaly, and spina bifida, has a long history. The most significant finding from these …
Primary prevention of neural-tube defects and some other major congenital abnormalities: recommendations for the appropriate use of folic acid during pregnancy
AE Czeizel - Paediatric drugs, 2000 - Springer
Neural-tube defects (NTDs) are common and serious congenital abnormalities of the central
nervous system. Although some cases of NTDs are induced by hyperhomocysteinaemia …
nervous system. Although some cases of NTDs are induced by hyperhomocysteinaemia …
Neural tube closure and neural tube defects: studies in animal models reveal known knowns and known unknowns
JB Wallingford - American Journal of Medical Genetics Part C …, 2005 - Wiley Online Library
The vertebrate central nervous system is a hollow structure that develops first as a flat sheet
of cells and subsequently rolls into a tube during embryogenesis. Failure of this rolling …
of cells and subsequently rolls into a tube during embryogenesis. Failure of this rolling …
Neural tube defects, vitamins and homocysteine
T Eskes - European journal of pediatrics, 1998 - Springer
Folic acid (multivitamins) reduce the recurrence and occurrence of neural tube defects
(NTDs). Vitamin profiles seem not suitable to identify women at risk for NTDs. A subset of …
(NTDs). Vitamin profiles seem not suitable to identify women at risk for NTDs. A subset of …