Spina bifida, anencephaly, and encephalocele are commonly grouped together and termed
neural tube defects (NTD). Failure of closure of the neural tube during development results …

Neural tube defects (NTDs) are serious malformations affecting approximately 1 per 1000
births, yet the mechanisms by which they arise are unknown. There have been consistent …

BACKGROUND: The number of mouse mutants and strains with neural tube closure defects
(NTDs) now exceeds 190, including 155 involving known genes, 33 with unidentified genes …

The number of mouse mutants and strains with neural tube defects (NTDs) now exceeds
240, including 205 representing specific genes, 30 for unidentified genes, and 9 …

Neural tube defects (NTDs) are common complex congenital malformations resulting from
failure of the neural tube closure during embryogenesis. It is established that folic acid …

The epidemiological investigation of the common open neural tube defects (NTDs),
anencephaly, and spina bifida, has a long history. The most significant finding from these …

Neural-tube defects (NTDs) are common and serious congenital abnormalities of the central
nervous system. Although some cases of NTDs are induced by hyperhomocysteinaemia …

The vertebrate central nervous system is a hollow structure that develops first as a flat sheet
of cells and subsequently rolls into a tube during embryogenesis. Failure of this rolling …

Folic acid (multivitamins) reduce the recurrence and occurrence of neural tube defects
(NTDs). Vitamin profiles seem not suitable to identify women at risk for NTDs. A subset of …

The formation of the embryonic brain and spinal cord begins as the neural plate bends to
form the neural folds, which meet and adhere to close the neural tube. The neural ectoderm …