Mangiferin attenuates renal ischemia-reperfusion injury by inhibiting inflammation and inducing adenosine production

B Wang, J Wan, X Gong, G Kuang, X Cheng… - International …, 2015 - Elsevier
Aim Ischemia reperfusion injury (IRI) is a leading cause of acute kidney injury, which is
associated with high morbidity. The aims of the present study were to examine whether …

Protective Effect of the Total Flavonoids from Rosa laevigata Michx Fruit on Renal Ischemia-Reperfusion Injury through Suppression of Oxidative Stress and …

L Zhao, L Xu, X Tao, X Han, L Yin, Y Qi, J Peng - Molecules, 2016 - mdpi.com
Renal ischemia-reperfusion injury (IRI) is a major cause of acute kidney injury (AKI). Our
previous studies have shown that the total flavonoids (TFs) from Rosa laevigata Michx fruit …

Curcumin alleviates lipopolysaccharide induced sepsis and liver failure by suppression of oxidative stress-related inflammation via PI3K/AKT and NF-κB related …

W Zhong, K Qian, J Xiong, K Ma, A Wang… - Biomedicine & …, 2016 - Elsevier
In many liver disorders, oxidative stress-related inflammation and apoptosis are important
pathogenic components, finally resulting in acute liver failure. Erythropoietin and its …

Curcumin relieved cisplatin-induced kidney inflammation through inhibiting Mincle-maintained M1 macrophage phenotype

RZ Tan, J Liu, YY Zhang, HL Wang, JC Li, YH Liu… - Phytomedicine, 2019 - Elsevier
Background Acute kidney injury (AKI) is a common kidney disease with a high risk of death
and can develop into chronic kidney disease (CKD) and renal failure eventually. Curcumin …

Protective effect of dapsone against renal ischemia-reperfusion injury in rat

S Nezamoleslami, M Sheibani… - …, 2020 - Taylor & Francis
Background: Ischemia/reperfusion can cause injury to tissues and compromise functionality
of organs due to inflammatory processes. Significantly, development of these effects in …

Effect of oleuropein on oxidative stress, inflammation and apoptosis induced by ischemia-reperfusion injury in rat kidney

H Nasrallah, I Aissa, C Slim, MA Boujbiha, MA Zaouali… - Life Sciences, 2020 - Elsevier
Aims This study aimed to evaluate the effect of oleuropein (OLE), the main phenolic
compound present in olive leaves, on kidney ischemia-reperfusion injury (IRI) and to explore …

Podocin, mTOR, and CHOP dysregulation contributes to nephrotoxicity induced of lipopolysaccharide/diclofenac combination in rats: Curcumin and silymarin could …

IH Hasan, A Badr, H Almalki, A Alhindi, HS Mostafa - Life sciences, 2023 - Elsevier
Aim Sepsis is a common cause of acute kidney injury (AKI). Lipopolysaccharides (LPS) are
the main gram-negative bacterial cell wall component with a well-documented inflammatory …

Naringenin alleviates renal ischemia reperfusion injury by suppressing er stress‐induced pyroptosis and apoptosis through activating nrf2/ho‐1 signaling pathway

B Zhang, S Wan, H Liu, Q Qiu, H Chen… - Oxidative Medicine …, 2022 - Wiley Online Library
Endoplasmic reticulum (ER) stress, pyroptosis, and apoptosis are critical molecular events in
the occurrence and progress of renal ischemia reperfusion (I/R) injury. Naringenin (4′, 5, 7 …

Oleanolic acid improves the symptom of renal ischemia reperfusion injury via the PI3K/AKT pathway

JR Yang, X Li, H Yang, C Long - Urologia Internationalis, 2021 - karger.com
Purpose: The aim of this study was to investigate the therapeutic effect of oleanolic acid (OA)
on the renal ischemia reperfusion injury (RIRI) and the possible mechanism. Methods: The …

7-hydroxycoumarin attenuates colistin-induced kidney injury in mice through the decreased level of histone deacetylase 1 and the activation of Nrf2 signaling pathway

J Wang, M Ishfaq, Q Fan, C Chen, J Li - Frontiers in Pharmacology, 2020 - frontiersin.org
Colistin has been considered as the last line of defense against Gram-negative bacterial
infections, however, the potential nephrotoxicity limited its clinical use. 7-Hydroxycoumarin …