Synteny conservation analysis is a well-established methodology to investigate the potential
functional role of unknown prokaryotic genes. However, bioinformatic tools to reconstruct …

Background Conserved gene context is used in many types of comparative genome
analyses. It is used to provide leads on gene function, to guide the discovery of regulatory …

The exploration and comparison of genome organization is routinely used in the frame of
genomic and phylogenomic analyses. As a consequence, in the past few years, various …

Motivation Comparing the organization of gene, gene clusters and their flanking genomic
contexts is of critical importance to the determination of gene function and evolutionary basis …

Background The procedural aspects of genome sequencing and assembly have become
relatively inexpensive, yet the full, accurate structural annotation of these genomes remains …

The analysis and comparison of gene neighborhoods is a powerful approach for exploring
microbial genome structure, function, and evolution. Although numerous tools exist for …

With the explosion of available genomic information, comparative genomics has become a
central approach to understanding microbial ecology and evolution. We developed DiGAlign …

Background Dynamic visualisation interfaces are required to explore the multiple microbial
genome data now available, especially those obtained by high-throughput sequencing …

Abstract Summary The Genome Context Viewer is a visual data-mining tool that allows
users to search across multiple providers of genome data for regions with similarly …

We have developed CiVi, a user-friendly web-based tool to create custom circular maps to
aid the analysis of microbial genomes and sequence elements. Sequence related data such …