A very broad definition of a tumor marker is: a tool that enables the clinician to answer
clinically relevant questions regarding a cancer disease (1). However, most researchers in …

Tumor markers are the molecules that indicate the presence or prognosis of malignancy.
Most often, tumor markers are produced by the cancer tissue itself. Many of them could be …

Tumor markers are molecules produced in the body in response to cancer. An ideal tumor
marker should have high sensitivity and specificity, should be cheap, and should be easily …

Background: Biological and technical advances have led to greatly increased research and
development of cancer biomarkers. This overview lists some of the challenges and barriers …

We present here for comment and constructive critical appraisal the first draft of the new
NACB Guidelines on the use of Tumor Markers in the clinic. The preparation of these draft …

There are few tumor markers that are clinically useful in predicting therapeutic responses or
patient outcomes despite nearly 20 years of advances in molecular biology. We discuss a …

Introduction of tumor markers into routine clinical practice has been poorly controlled, with
few criteria or guidelines as to how such markers should be used. We propose a Tumor …

Tumor Markers in Cancer Diagnosis and Prognosis Page 1 Introduction A tumor marker is a
biochemical indicator for the presence of a tumor. In clinical usage, the term usually refers to a …

A tumor biomarker is a molecular or process-based change that reflects the status of an
underlying malignancy. A tumor biomarker may be identified and measured by one or more …

Reviewing the literature it would appear that tumor markers have often flattered to deceive.
Early promise does not often seem to be borne out in extended trials. Despite apparently …