Multiple complications associated with mechanical ventilation mandate that clinicians
expeditiously define and reverse the pathophysiologic processes that precipitate respiratory …

Recent findings are shedding more light on this topic, and transforming 'the artistic'aspect of
weaning and liberation from mechanical ventilation into a more 'scientific'approach that will …

Mechanical ventilation is the defining event of intensive care unit (ICU) management.
Although it is a life saving intervention in patients with acute respiratory failure and other …

For a small but important fraction of patients receiving mechanical ventilation, protracted
dependence on a ventilator entails serious hazard, disability, and cost. Most such patients …

Med 2017; 195: 120–133. http://dx. doi. org/10.1164/rccm. 201610-2075ST (2) 3) Ouellette
DR, Patel S, Girard TD, Morris PE, Schmidt GA, Truwit JD, Alhazzani W, Burns SM, Epstein …

This article reviews the factors that determine a patient's ability to resume spontaneous
breathing following a period of mechanical ventilation, the use of physiologic measurements …

The development of acute ventilatory failure represents an inability of the respiratory control
system to maintain a level of respiratory motor output to cope with the metabolic demands of …

Background This clinical practice guideline addresses six questions related to liberation
from mechanical ventilation in critically ill adults. It is the result of a collaborative effort …

Use of mechanical ventilation is associated with several major complications despite its
lifesaving potential. Timely discontinuation of mechanical ventilation is critical to control of …

Patients require mechanical ventilatory support when the ventilatory and/or gas exchange
capabilities of their respiratory system fail. This failure can be the result of processes both …