Background: Different volatile anesthetic agents have differing propensities for inducing
seizures. A measure of the predilection to develop seizures is the presence of interictal spike …

The cerebral effects of sevoflurane were compared in dogs with those of enflurane and
isoflurane. Initially, the minimum alveolar concentrations (MAC) of sevoflurane and …

The effects of 0.5-2.0 MAC (3.6-15%) desflurane on cerebral function, metabolism, and
hemodynamics and on systemic metabolism and hemodynamics were examined in dogs …

Desflurane causes dose-dependent decreases in cerebrovascular resistance and cerebral
metabolic rate of oxygen consumption (CMRO2), suggesting that desflurane is a cerebral …

The electroencephalographic (EEG) effects of a new inhaled anesthetic are of interest
because of the potential of such agents to produce excitatory (convulsant) activity and …

Six dogs initially anaesthetized with isoflurane–N2O–O2 for surgery with cannulation of the
sinus sagittalis for direct measurement of cerebral blood flow (CBF) and maintained with 1 …

The electrophysiologic effects of sevoflurane are not well characterized in humans. Among
patients with refractory epilepsy, this study compared 1) electroencephalographic (EEG) …

IMPLICATIONS: A rapid increase in the concentration of sevoflurane induces epileptiform
encephalogram (EEG) with tachycardia. A rapid increase in the concentration of desflurane …

Desflurane is a potent inhaled anesthetic associated with a dose-dependent depression of
cortical electrical activity. Recently, it has been suggested that the burst suppression pattern …

Background: In clinical neuroanaesthesia, the increase in cerebral blood flow (CBF) and
intracranial pressure caused by the cerebral vasodilative effects of an inhalational …