Asiatic acid attenuates tubular injury in diabetic kidney disease by regulating mitochondrial dynamics via the Nrf-2 pathway

Y Ji, X Zhang, J Chen, S Song, S Fang, Z Wang, S Xu… - Phytomedicine, 2023 - Elsevier
Background Mitochondrial dynamics plays a crucial role in tubular injury in diabetic kidney
disease (DKD). Asiatic acid (AA) has demonstrated renal protective effects in DKD; however …
被引用次数：4 相关文章 所有 4 个版本
[HTML] sciencedirect.com

[HTML][HTML] Advances in the pharmacological study of Chinese herbal medicine to alleviate diabetic nephropathy by improving mitochondrial oxidative stress

M Chen, Y Chen, W Zhu, X Yan, J Xiao, P Zhang… - Biomedicine & …, 2023 - Elsevier
Diabetic nephropathy (DN) is one of the serious complications of diabetes mellitus, primarily
arising from type 2 diabetes (T2DM), and can progress to chronic kidney disease (CKD) and …
被引用次数：6 相关文章 所有 3 个版本

JinChan YiShen TongLuo Formula ameliorate mitochondrial dysfunction and apoptosis in diabetic nephropathy through the HIF-1α-PINK1-Parkin pathway

X Zhang, J Guo, Y Wang, Y Jiang, S Li, YN Liu… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance The JinChan YiShen TongLuo (JCYSTL) formula,
a traditional Chinese medicine (TCM), has been used clinically for decades to treat diabetic …
被引用次数：2 相关文章 所有 4 个版本
[HTML] frontiersin.org

[HTML][HTML] Berberine reduces lipid accumulation by promoting fatty acid oxidation in renal tubular epithelial cells of the diabetic kidney

Q Rong, B Han, Y Li, H Yin, J Li, Y Hou - Frontiers in pharmacology, 2022 - frontiersin.org
Abnormal lipid metabolism in renal tubular epithelial cells contributes to renal lipid
accumulation and disturbed mitochondrial bioenergetics which are important in diabetic …
被引用次数：27 相关文章 所有 5 个版本
[HTML] plos.org

[HTML][HTML] Astragaloside IV ameliorates diabetic nephropathy by modulating the mitochondrial quality control network

X Liu, W Wang, G Song, X Wei, Y Zeng, P Han… - PloS one, 2017 - journals.plos.org
The aim of this study was to investigate the effect and possible mechanism of Astragaloside
IV (AS-IV) on retarding the progression of diabetic nephropathy (DN) in a type 2 diabetic …
被引用次数：67 相关文章 所有 9 个版本
[HTML] frontiersin.org

[HTML][HTML] ShenQiWan ameliorates renal injury in type 2 diabetic mice by modulating mitochondrial fusion and endoplasmic reticulum stress

W Xiong, J Feng, Y Liu, J Liu, L Fu, Q Wang… - Frontiers in …, 2023 - frontiersin.org
Background: ShenQiWan is commonly used in traditional Chinese medicine for the
treatment of diabetic nephropathy, which is closely related to mitochondrial fusion and …
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[HTML] tandfonline.com

4-Octyl itaconate attenuates renal tubular injury in db/db mice by activating Nrf2 and promoting PGC-1α-mediated mitochondrial biogenesis

M Shao, J Chen, F Zhang, Q Su, X Lin, W Wang… - Renal …, 2024 - Taylor & Francis
Objectives: The aim of this study was to investigate the mechanism of itaconate's potential
effect in diabetic kidney disease. Methods: Renal immune responsive gene 1 (IRG1) levels …
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[HTML] nih.gov

[HTML][HTML] Artemether improves type 1 diabetic kidney disease by regulating mitochondrial function

Y Wang, P Han, M Wang, W Weng, H Zhan… - American Journal of …, 2019 - ncbi.nlm.nih.gov
Many patients with type 1 diabetes mellitus suffer from progressive diabetic kidney disease
(DKD). The progression of DKD is largely attributed to mitochondrial dysfunction, with key …
被引用次数：16 相关文章 所有 5 个版本
[HTML] frontiersin.org

[HTML][HTML] Formononetin attenuates renal tubular injury and mitochondrial damage in diabetic nephropathy partly via regulating sirt1/PGC-1α pathway

Q Huang, H Chen, K Yin, Y Shen, K Lin… - Frontiers in …, 2022 - frontiersin.org
Mitochondrial abnormality is one of the main factors of tubular injury in diabetic nephropathy
(DN). Formononetin (FMN), a novel isoflavonoid isolated from Astragalus membranaceus …
被引用次数：23 相关文章 所有 7 个版本
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Huangqi‐Danshen decoction ameliorates adenine‐induced chronic kidney disease by modulating mitochondrial dynamics

X Liu, S Huang, F Wang, L Zheng, J Lu… - Evidence‐Based …, 2019 - Wiley Online Library
Chronic kidney disease (CKD) is a leading public health problem with high morbidity and
mortality. However, the therapies remain limited. Traditional Chinese medicine (TCM) has …
被引用次数：22 相关文章 所有 9 个版本