Renal angiotensin II concentration and interstitial infiltration of immune cells are correlated with blood pressure levels in salt-sensitive hypertension

M Franco, F Martínez, Y Quiroz… - American Journal …, 2007 - journals.physiology.org
Renal immune cell infiltration and cells expressing angiotensin II (AII) in tubulointerstitial
areas of the kidney are features of experimental models of salt-sensitive hypertension …

Pathophysiology of salt-sensitive hypertension: a new scope of an old problem

M Franco, LG Sanchez-Lozada, R Bautista… - Blood purification, 2008 - karger.com
It has been recognized for many years that salt intake is one of the main environmental
factors responsible for the development of hypertension. More than 30 years ago, Guyton …

Impaired pressure natriuresis resulting in salt-sensitive hypertension is caused by tubulointerstitial immune cell infiltration in the kidney

M Franco, E Tapia, R Bautista… - American Journal …, 2013 - journals.physiology.org
Immune cell infiltration of the kidney is a constant feature in salt-sensitive hypertension
(SSHTN). We evaluated the relationship between the renal inflammation and pressure …

Angiotensin II, interstitial inflammation, and the pathogenesis of salt-sensitive hypertension

M Franco, F Martínez… - American Journal …, 2006 - journals.physiology.org
Transient administration of ANG II causes persistent salt-sensitive hypertension associated
with arteriolopathy, interstitial inflammation, and cortical vasoconstriction; blocking the …

The role of immune cells infiltrating the kidney in the pathogenesis of salt-sensitive hypertension.

B Rodríguez-Iturbe, Y Quiroz… - … : Official Journal of the …, 2002 - europepmc.org
This work summarizes recent evidence that suggests that renal infiltration with immune cells
plays a role in the pathogenesis of salt-sensitive hypertension. The presence of …

Role of immune factors in angiotensin II-induced hypertension and renal damage in Dahl salt-sensitive rats

B Wade, G Petrova, DL Mattson - American Journal of …, 2018 - journals.physiology.org
The present study assessed the importance of immunity in angiotensin (ANG) II (5 ng· kg− 1·
min− 1 iv)-mediated hypertension in Dahl salt-sensitive (SS) rats and SS rats deficient in T …

Infiltrating immune cells in the kidney in salt-sensitive hypertension and renal injury

DL Mattson - American Journal of Physiology-Renal …, 2014 - journals.physiology.org
The importance of the immune system in hypertension, vascular disease, and renal disease
has been appreciated for over 50 years. Recent experimental advances have led to a …

Intrarenal angiotensin II is associated with inflammation, renal damage, and dysfunction in dahl salt-sensitive hypertension

L Lin, WE Phillips, RD Manning Jr - Journal of the American society of …, 2009 - Elsevier
The goal of this study was to test the hypothesis that intrarenal angiotensin (Ang) II has a
proinflammatory effect leading to renal damage and dysfunction in Dahl salt-sensitive (S) …

[HTML][HTML] Mycophenolate mofetil prevents salt-sensitive hypertension resulting from angiotensin II exposure

B Rodríguez-Iturbe, H Pons, Y Quiroz, K Gordon… - Kidney international, 2001 - Elsevier
Mycophenolate mofetil prevents salt-sensitive hypertension resulting from angiotensin II
exposure. Background Interstitial mononuclear cell infiltration is a feature of experimental …

Role of afferent and efferent renal nerves in the development of Ang II‐salt hypertension in rats

JD Foss, J Fiege, Y Shimizu, JP Collister… - Physiological …, 2018 - Wiley Online Library
Hypertension is the leading modifiable risk factor for death worldwide, yet the causes remain
unclear and treatment remains suboptimal. Catheter‐based renal denervation (RDNX) is a …