Biological basis for increased sensitivity to radiation therapy in HPV‐positive head and neck cancers

V Bol, V Grégoire - BioMed research international, 2014 - Wiley Online Library
Although development of head and neck squamous cell carcinomas (HNSCCs) is commonly
linked to the consumption of tobacco and alcohol, a link between human papillomavirus …

Increased radiosensitivity of HPV-positive head and neck cancers: Molecular basis and therapeutic perspectives

H Mirghani, F Amen, Y Tao, E Deutsch, A Levy - Cancer treatment reviews, 2015 - Elsevier
Human papillomavirus driven head and neck squamous cell carcinoma (HNSCC),
particularly oropharyngeal squamous cell carcinoma (OPSCC), are characterized by a …

Modulation of therapeutic sensitivity by human papillomavirus

AD Swick, A Chatterjee, AMA De Costa… - Radiotherapy and …, 2015 - Elsevier
Human papillomaviruses (HPVs) are small double-stranded DNA viruses that pose
significant public health concerns as the causative agent of approximately 5% of worldwide …

Biomarkers of radioresistance in head and neck squamous cell carcinomas

D Avril, JP Foy, J Bouaoud, V Grégoire… - International Journal of …, 2023 - Taylor & Francis
Purpose Head and neck squamous cell carcinoma (HNSCC) is a major cause of morbidity
and mortality. Although HNSCC is mainly caused by tobacco and alcohol consumption …

Enhanced radiation sensitivity of human papillomavirus-driven head and neck cancer: focus on immunological aspects

M Özcan-Wahlbrink, C Schifflers… - Frontiers in …, 2019 - frontiersin.org
Head and neck squamous cell carcinomas (HNSCC), emerging in the mucosa of the upper
aerodigestive tract, are associated with either the classical risk factors, tobacco and alcohol …

Biological features of human papillomavirus-related head and neck cancers contributing to improved response

C Cleary, JE Leeman, DS Higginson, N Katabi… - Clinical Oncology, 2016 - Elsevier
Head and neck squamous cell carcinomas (HNSCC) are the sixth most common malignancy
globally, and an increasing proportion of oropharyngeal HNSCCs are associated with the …

Enhanced radiation sensitivity in HPV-positive head and neck cancer

RJ Kimple, MA Smith, GC Blitzer, AD Torres, JA Martin… - Cancer research, 2013 - AACR
Patients with human papillomavirus (HPV+)–associated head and neck cancer (HNC) show
significantly improved survival outcome compared with those with HPV-negative (HPV−) …

HPV-induced oropharyngeal cancer, immune response and response to therapy

HL Vu, AG Sikora, S Fu, J Kao - Cancer letters, 2010 - Elsevier
Approximately 25% of head and neck squamous cell carcinoma (HNSCC) worldwide are
associated with high-risk human papillomaviruses (HPV). HPV-positive HNSCCs have a …

Increased radiosensitivity of HPV-positive head and neck cancer cell lines due to cell cycle dysregulation and induction of apoptosis

A Arenz, F Ziemann, C Mayer, A Wittig… - Strahlentherapie und …, 2014 - Springer
Abstract Background and purpose Human Papillomavirus (HPV)-related head and neck
squamous cell carcinoma (HNSCC) respond favourably to radiotherapy as compared to …

The molecular mechanisms of increased radiosensitivity of HPV-positive oropharyngeal squamous cell carcinoma (OPSCC): an extensive review

C Liu, D Mann, UK Sinha… - Journal of Otolaryngology …, 2018 - journals.sagepub.com
Head and neck carcinomas (HNCs) collectively are the sixth most common cancer with an
annual incidence of about 400,000 cases in the US. The most well-established risk factors …