Measurement of Outflow Facility Using iPerfusion

JM Sherwood, E Reina-Torres, JA Bertrand, B Rowe… - PloS one, 2016 - journals.plos.org
Elevated intraocular pressure (IOP) is the predominant risk factor for glaucoma, and
reducing IOP is the only successful strategy to prevent further glaucomatous vision loss. IOP …

Vascular aspects in the pathophysiology of glaucomatous optic neuropathy

HS Chung, A Harris, DW Evans, L Kagemann… - Survey of …, 1999 - Elsevier
Glaucoma remains a major eye illness with unknown etiology. Although elevated intraocular
pressure is clearly a major risk factor, vascular deficits may contribute to initiation and …

Clinical evaluation of the aqueous outflow system in primary open-angle glaucoma for canaloplasty

MC Grieshaber, A Pienaar, J Olivier… - … & visual science, 2010 - iovs.arvojournals.org
Purpose.: To assess the aqueous outflow pathway in primary open-angle glaucoma (POAG)
through provocative gonioscopy and channelography with a flexible microcatheter and …

A trabecular bypass flow hypothesis

J Zhou, GT Smedley - Journal of glaucoma, 2005 - journals.lww.com
Purpose: To introduce a hypothesis that theorizes the effect of a trabecular bypass, a
channel created through the trabecular meshwork, on the facility of outflow and the …

Direct involvement of trabecular meshwork in the regulation of aqueous humor outflow

M Wiederholt - Current opinion in ophthalmology, 1998 - journals.lww.com
Our new hypothesis for the regulation of aqueous humor outflow suggests that the trabecular
meshwork is not a passive filter but an active contractile element contributing to the ciliary …

Mechanical responsiveness of the endothelial cell of Schlemm's canal: scope, variability and its potential role in controlling aqueous humour outflow

EH Zhou, R Krishnan, WD Stamer… - Journal of The …, 2012 - royalsocietypublishing.org
Primary open-angle glaucoma is associated with elevated intraocular pressure, which in
turn is believed to result from impaired outflow of aqueous humour. Aqueous humour outflow …

[HTML][HTML] Increased endoplasmic reticulum stress in human glaucomatous trabecular meshwork cells and tissues

JC Peters, S Bhattacharya, AF Clark… - … & visual science, 2015 - jov.arvojournals.org
Purpose.: Primary open-angle glaucoma (POAG) is the most common form of glaucoma and
is accompanied by elevated intraocular pressure (IOP) resulting from increased aqueous …

[HTML][HTML] Effect of general anesthetics on IOP in rats with experimental aqueous outflow obstruction

L Jia, WO Cepurna, EC Johnson… - … ophthalmology & visual …, 2000 - arvojournals.org
purpose. To determine the effect of several common general anesthetics on intraocular
pressure (IOP) after experimental aqueous outflow obstruction in the rat. methods. A single …

Dysfunctional regulation of ocular blood flow: A risk factor for glaucoma?

D Moore, A Harris, D WuDunn, N Kheradiya… - Clinical …, 2008 - Taylor & Francis
Primary open angle glaucoma (OAG) is a multifactorial optic neuropathy characterized by
progressive retinal ganglion cell death and associated visual field loss. OAG is an emerging …

The role of Schlemm's canal in aqueous outflow from the human eye.

MC Johnson, RD Kamm - Investigative ophthalmology & visual …, 1983 - iovs.arvojournals.org
A mathematical model of Schlemm's canal is developed to simulate collapse of the canal
and its effect on resistance to flow through the aqueous outflow network. Schlemm's canal is …