Rational design of hybrid peptides: a novel drug design approach

C Wang, C Yang, Y Chen, L Ma, K Huang - Current medical science, 2019 - Springer
Peptides play crucial roles in various physiological and pathological processes.
Consequently, the investigation of peptide-based drugs is a highlight in the research and …

Selected application of peptide molecules as pharmaceutical agents and in cosmeceuticals

M Negahdaripour, H Owji, M Eslami… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Peptide molecules are being vastly investigated as an emerging class of
therapeutic molecules in recent years. Currently, 60 peptides have been approved by the …

Strategic approaches to improvise peptide drugs as next generation therapeutics

P Barman, S Joshi, S Sharma, S Preet… - International journal of …, 2023 - Springer
In recent years, the occurrence of a wide variety of drug-resistant diseases has led to an
increase in interest in alternate therapies. Peptide-based drugs as an alternate therapy hold …

Strategies to Improve the Activity and Biocompatibility: Modification of Peptide Antibiotics

J Zhang, J Zhang, Y Wang, X Zhang… - Foodborne Pathogens …, 2022 - liebertpub.com
As host defense peptides, peptide antibiotics exist in almost all organisms. Many of their
activities come from their inactivation of bacteria, yeast, fungi, and even cancer cells …

Computational resources for designing peptide based drugs preferred in the field of nanomedicine

B Senthilkumar, R Rajasekaran - Journal of Bionanoscience, 2016 - ingentaconnect.com
Discovery of peptides used in protein therapeutics proposes treatment for a wide range of
infectious and chronic human diseases. Therapeutically significant peptides are developed …

Peptide-based therapeutics in cancer therapy

AT Jalil, MA Abdulhadi, LR Al-Ameer, WM Taher… - Molecular …, 2023 - Springer
A monster called cancer is still one of the most challenging human problems and one of the
leading causes of death in the world. Different types of treatment methods are used for …

Peptides with dual antimicrobial–anticancer activity: Strategies to overcome peptide limitations and rational design of anticancer peptides

Y Liscano, J Oñate-Garzón, JP Delgado - Molecules, 2020 - mdpi.com
Peptides are naturally produced by all organisms and exhibit a wide range of physiological,
immunomodulatory, and wound healing functions. Furthermore, they can provide with …

Peptide based antimicrobials: Design strategies and therapeutic potential

PK Hazam, R Goyal, V Ramakrishnan - Progress in biophysics and …, 2019 - Elsevier
Therapeutic activity of antibiotics is noteworthy, as they are used in the treatment of microbial
infections. Regardless of their utility, there has been a steep decrease in the number of drug …

Peptide‐based supramolecular therapeutics for fighting major diseases

Z Wang, H Luo, H Wang, M Xiao, H Jia… - Advanced Functional …, 2024 - Wiley Online Library
Peptide‐based supramolecular therapeutics (PST) refer to those theranostic nanomedicines
based on peptide or peptide derivatives self‐assembly that are constructed in vitro or in vivo …

Peptide-based drug design: here and now

L Otvos - Peptide-based drug design, 2008 - Springer
After many years of stagnation, peptide therapeutics once again became the focus of
innovative drug development efforts backed up by venture funds and biotechnology …