Red ginseng has stronger anti-aging effects compared to ginseng possibly due to its regulation of oxidative stress and the gut microbiota

X Peng, M Hao, Y Zhao, Y Cai, X Chen, H Chen… - Phytomedicine, 2021 - Elsevier
Background Panax ginseng (PG) and red ginseng (RG) are considered to be effective anti-
aging treatments. However, evidence of their therapeutic mechanisms and difference in anti …

Ginseng under forest exerts stronger anti-aging effects compared to garden ginseng probably via regulating PI3K/AKT/mTOR pathway, SIRT1/NF-κB pathway and …

M Hao, C Ding, X Peng, H Chen, L Dong, Y Zhang… - Phytomedicine, 2022 - Elsevier
Background Ginseng is deemed to be an effective anti-aging therapy. Evidence for
differences in representative active ingredients and anti-aging effects between garden …

Evaluating the effects of mitochondrial autophagy flux on ginsenoside Rg2 for delaying D-galactose induced brain aging in mice

J Zhang, K Chen, Y Zhou, H Wei, M Qi, Z Wang… - Phytomedicine, 2022 - Elsevier
Background Aging is an inevitable gradual process of the body, which can cause
dysfunction or degeneration of the nervous or immune system, thus becoming a critical …

Effects of Guilingji on aging rats and its underlying mechanisms

S Zhao, X Liu, J Tian, X Gao, H Liu, G Du… - Rejuvenation …, 2020 - liebertpub.com
Guilingji (GLJ), a traditional Chinese medicine, is of wide concern because of its remarkable
antiaging effect with a long application history. It mainly consists of traditional Chinese …

[HTML][HTML] Ginseng improves cognitive deficit via the RAGE/NF-κB pathway in advanced glycation end product-induced rats

X Tan, J Gu, B Zhao, S Wang, J Yuan, C Wang… - Journal of ginseng …, 2015 - Elsevier
Background Ginseng, the root of Panax ginseng (PG), is used widely as a herbal medicine
to prevent and treat various diseases. Panax ginseng has pharmacological effects on …

[HTML][HTML] Korean Red Ginseng exerts anti-inflammatory and autophagy-promoting activities in aged mice

JK Kim, KK Shin, H Kim, YH Hong, W Choi… - Journal of Ginseng …, 2021 - Elsevier
Abstract Background Korean Red Ginseng (KRG) is a traditional herb that has several
beneficial properties including anti-aging, anti-inflammatory, and autophagy regulatory …

[HTML][HTML] Administration of red ginseng ameliorates memory decline in aged mice

Y Lee, S Oh - Journal of ginseng research, 2015 - Elsevier
Background It has been known that ginseng can be applied as a potential nutraceutical for
memory impairment; however, experiments with animals of old age are few. Methods To …

[HTML][HTML] Research progress on the anti-aging potential of the active components of ginseng

J Su, Q Su, S Hu, X Ruan, S Ouyang - Nutrients, 2023 - mdpi.com
Aging is a cellular state characterized by a permanent cessation of cell division and evasion
of apoptosis. DNA damage, metabolic dysfunction, telomere damage, and mitochondrial …

[HTML][HTML] Ginsenoside Rg1 ameliorates the cognitive deficits in D-galactose and AlCl3-induced aging mice by restoring FGF2-Akt and BDNF-TrkB signaling axis to …

SJ Zhong, L Wang, RZ Gu, WH Zhang… - International journal of …, 2020 - ncbi.nlm.nih.gov
Ginsenoside Rg1 is the main active ingredient of Panax ginseng with the activity of
neuroprotective, antioxidant and strengthening the immune system. Therefore, we …

[HTML][HTML] Ginsenoside Rg1 prevents cognitive impairment and hippocampus senescence in a rat model of D-galactose-induced aging

J Zhu, X Mu, J Zeng, C Xu, J Liu, M Zhang, C Li… - PloS one, 2014 - journals.plos.org
Neurogenesis continues throughout the lifetime in the hippocampus, while the rate declines
with brain aging. It has been hypothesized that reduced neurogenesis may contribute to age …