Exposure assessment serves as a pivotal component in the risk evaluation of organic
chemicals. Precise evaluation of the potential hazards posed by these chemicals to animals …

Toxicity is usually investigated using a set of standardized animal-based studies which,
unfortunately, fail to detect all compounds that induce human adverse events and do not …

Chemicals are essential components of our everyday life, from industrial chemicals used for
manufacturing processes to the active principles of pharmaceuticals. As a consequence …

Economic growth and development come with increasing use of chemicals and subsequent
exposure of humans both in professional and in consumer environments. Exposure to …

With the increasing variety and quantity of chemicals entering into the environment,
chemical risk assessment is meeting more and more challenges. The traditional risk …

It is still a major challenge to protect humans at workplaces and in the environment. To cope
with this task, it is a prerequisite to obtain detailed information on the extent of chemical …

This book presents the frontier research of toxicology and health risk assessment of
chemicals. First, it provides an overview of the current methods of evaluating safety amounts …

Over the last decade, several large-scale United States and international programs have
been initiated to incorporate advances in molecular and cellular biology,-omics …

The tremendous progress in the development of new technologies in the areas of molecular
biology and bioinformatics enables interrogation of cellular responses to toxicant treatment …

To reduce the considerable investments of toxicity testing and protecting animal welfare, a
new toxicity testing strategy based on response pathways of human cell lines has been …