Vascular endothelial growth factor (VEGF) is an endothelial cell-specific mitogen with potent
angiogenic and vascular permeability-inducing properties, both of which may be important …

The formation of new microvasculature by capillary sprouting at the site of islet
transplantation is crucial for the long-term survival and function of the graft. Vascular …

Background. Vascular endothelial growth factor (VEGF) and its two receptor tyrosine
kinases, Flk-1/KDR and Flt-1, may play an important role in mediating the revascularization …

Successful islet transplantation depends on the infusion of sufficiently large quantities of
islets, of which only∼ 30% become stably engrafted. Rapid and adequate revascularization …

Background. Blood flow is impaired in islet transplants, but there is conflicting evidence on
improving the outcome by promoting vascularization. We previously reported that islet …

We have reported that vascular endothelial growth factor (VEGF) promotes the
revascularization of transplanted islets, thereby reducing the initial number required to …

Aims/hypothesis Rapamycin, part of the immunosuppressive regimen of the Edmonton
protocol, has been shown to inhibit vascular endothelial growth factor (VEGF) production …

To investigate molecular mechanisms controlling islet vascularization and revascularization
after transplantation, we examined pancreatic expression of three families of angiogenic …

AIM: To determine whether the elevated vascular endothelial growth factor (VEGF)
expression produced by the transfected vascular endothelial cells (VECs) could stimulate …

Background. The aim of this study was to analyze the role of vascular endothelial growth
factor (VEGF) binding to its high-affinity receptor kinase insert domain (KDR)-containing …