In rats, a distinct environment repeatedly paired with nicotine (0.421 mg/kg base, sc) comes
to evoke an increase in activity in the absence of any drug. This hyperactivity indicates a …

Little is known about the processes that mediate acquisition and expression of conditioned
associations between contextual cues and psychomotor effects of nicotine. In four separate …

We have investigated the effects of environmental conditioning on the induction of nicotine
sensitization of locomotion, stereotypy and nucleus accumbens dopamine release. Sprague …

Rats were trained to discriminate 1.9 μmol/kg (−)-nicotine (0.3 mg/kg) from saline in a
standard two-bar operant conditioning paradigm with food reinforcement. The effect of …

Rationale Previous research has determined that rats reared in an enriched condition (EC)
are more sensitive to the effects of acute systemic amphetamine than rats raised in an …

The effects of contextual conditioning on the induction of nicotine sensitization of locomotor
activity, stereotypy and nucleus accumbens dopamine release were studied using a 15-day …

Rats were given daily injections of nicotine sulfate in doses ranging from 0.1 to 0.4 mg/kg.
The behavioral effect of these injections was measured as locomotor activity in photocell …

In rats, the pharmacological (interoceptive) effects of 0.4 mg/kg nicotine can serve as a
conditional stimulus in a Pavlovian conditioning task. Nicotine administration is paired with …

As failure to induce behavioral dependence to oral nicotine (0.31 mM) might be caused by
taste aversion. Sixteen rats were presented nicotine around the taste aversion threshold …

Nicotine tartrate (2 mg/kg), and a nicotinic agonist, RJR 2403 (1.4 mg/kg), and antagonist,
mecamylamine (1 mg/kg), were administered to separate groups of rats SC twice daily for 10 …