Di-2-ethylhexyl phthalate induces heart looping disorders during zebrafish development

Y Sun, F Yang, Y Liu, M Yu, F Wu… - … and Industrial Health, 2021 - journals.sagepub.com
Di-2-ethylhexyl phthalate (DEHP) is a type of plasticizer widely used in industry. It is well-
known for its toxic effects to endocrine and reproductive systems and has been detected in …

Toxicity assessment of di (2-ethylhexyl) phthalate using zebrafish embryos: Cardiotoxic potential

A Naïja, Y Horie, S Boughattas, S Ismail… - … and Physiology Part C …, 2024 - Elsevier
Plasticizers are considered as newly emerged contaminants. They are added to plastics to
increase their flexibility and softness. Phthalate plasticizers including the Di-2-ethylhexyl …

Exposure to DBP induces the toxicity in early development and adverse effects on cardiac development in zebrafish (Danio rerio)

G Sun, Y Li - Chemosphere, 2019 - Elsevier
Dibutyl phthalate (DBP) is one of the most ubiquitous plasticizers used worldwide and has
been frequently detected in soil, water, atmosphere, and other environmental media. DBP …

[HTML][HTML] Review on toxic effects of Di (2-ethylhexyl) phthalate on zebrafish embryos

WS Kwan, VAL Roy, KN Yu - Toxics, 2021 - mdpi.com
Di (2-ethylhexyl) phthalate (DEHP) is widely used as a plasticizer in consumer products.
People are continuously exposed to DEHP through ingestion, inhalation and dermal …

The effect of maternal exposure to di‐(2‐ethylhexyl)‐phthalate on fetal cardiac development in mice

C Tang, Y Deng, H Duan, Y Zhang, Y Li… - Journal of Applied …, 2018 - Wiley Online Library
Accumulating evidence has suggested a link between maternal di‐(2‐ethylhexyl)‐phthalate
(DEHP) exposure and various developmental abnormalities. However, the evidence …

Developmental toxicity and cardiac effects of butyl benzyl phthalate in zebrafish embryos

G Sun, K Liu - Aquatic toxicology, 2017 - Elsevier
Phthalic acid esters (PAEs), commonly called phthalates, have become ubiquitous
environment pollutants. Studies have focused on reproductive toxicity, neurotoxicity …

A multi-omics approach reveals molecular mechanisms by which phthalates induce cardiac defects in zebrafish (Danio rerio)

X Mu, X Chen, J Liu, L Yuan, D Wang, L Qian… - Environmental …, 2020 - Elsevier
The potential risks of phthalates affecting human and animal health as well as the
environment are emerging as serious concerns worldwide. However, the mechanism by …

Effects of di-(2-ethylhexyl) phthalate (DEHP) on behavior and dopamine signaling in zebrafish (Danio rerio)

W Huang, J Xiao, X Shi, S Zheng, H Li, C Liu… - Environmental …, 2022 - Elsevier
Abstract Di (2-ethylhexyl) phthalate (DEHP) is a widely used plasticizer, also known as a
developmental toxicant, but its neurobehavioral toxicity remains elusive. This study …

Bis-(2-ethylexhyl) phthalate impairs spermatogenesis in zebrafish (Danio rerio)

B Corradetti, A Stronati, L Tosti, G Manicardi… - Reproductive …, 2013 - Elsevier
Abstract Bis-(2-ethylhexyl) phthalate (DEHP) is a widely used industrial additive for
increasing plastic flexibility. Its metabolites are known to exert toxic effects on reproduction …

Effects of phthalate acid esters on zebrafish larvae: Development and skeletal morphogenesis

SY Pu, N Hamid, YW Ren, DS Pei - Chemosphere, 2020 - Elsevier
This study evaluated the acute developmental toxicity of six priority phthalic acid esters
(PAEs) including dimethyl phthalate (DMP), diethyl phthalate (DEP), dibutyl phthalate (DBP) …