ABSTRACT SARS-CoV-2 anti-spike antibody concentrations and angiotensin converting
enzyme-2 (ACE-2) inhibition have been used as surrogates to live viral neutralizing antibody …

The accurate measurement of serological response to SARS-CoV-2 vaccination is needed
to correlate responses with effective protective immunity. The World Health Organization …

Abstract Background The SARS-CoV-2 virus has mutated and evolved since the inception of
the COVID-19 pandemic bringing into question the future effectiveness of current vaccines …

Background Measuring anti-viral antibody affinity in blood plasma or serum is a rational
quantitative approach to assess humoral immune response and acquired protection. Three …

Numerous vaccines have been generated to decrease the morbidity and mortality of COVID-
19. This study aims to evaluate the immunogenicity of the heterologous boosts by BioNTech …

Background We studied whether comorbid conditions affect strength and duration of
immune responses after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Background Recent reports have suggested that among individuals previously infected with
SARS-CoV-2, a single mRNA vaccine dose is sufficient to elicit high levels of immunity …

Background With rapid approval of SARS-CoV-2 vaccines, the ability of clinical laboratories
to detect vaccine-induced antibodies with available high-throughput commercial assays is …

Newly emerged pathogens such as SARS-CoV-2 highlight the urgent need for assays that
detect levels of neutralizing antibodies that may be protective. We studied the relationship …

Background Data on the development of neutralizing antibodies (nAbs) against SARS-CoV-
2 after SARS-CoV-2 infection and after vaccination with mRNA COVID-19 vaccines are …